{"id":"W2074059573","doi":"10.1002/bab.1006","title":"Large‐scale production of human mesenchymal stem cells for clinical applications","year":2012,"lang":"en","type":"review","venue":"Biotechnology and Applied Biochemistry","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Calgary","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Mesenchymal stem cell; Platelet lysate; Fetal bovine serum; Regenerative medicine; Microcarrier; Biotechnology; Tissue engineering; Stem cell; Biochemical engineering; Computer science; Medicine; Biomedical engineering; Biology; Cell culture; Cell biology; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008720272,0.000362864,0.001625113,0.0001471632,0.0001484628,0.000006796427,0.0002805217,0.002662802,0.00002793678],"category_scores_gemma":[0.00002235014,0.0002969299,0.0003342838,0.0003331403,0.0006509243,0.00001106718,0.0002406795,0.000943846,0.0000242009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005774523,"about_ca_system_score_gemma":0.0001936675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.595151e-7,"about_ca_topic_score_gemma":3.95114e-7,"domain_scores_codex":[0.9975378,0.00002994479,0.0009165744,0.0008380477,0.0001984038,0.0004792597],"domain_scores_gemma":[0.998212,0.0001257393,0.0004752596,0.0009166414,0.00008430648,0.0001860248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000474047,0.0007061065,0.00002359222,0.06429724,0.0002994672,0.000001101277,0.00001430786,3.697958e-9,0.05609705,0.001029985,0.001279924,0.8762038],"study_design_scores_gemma":[0.0003473306,0.00009037727,0.000001292276,0.0008227514,0.0008245301,0.00004782867,0.000111166,2.866989e-7,0.2335812,0.00002728009,0.7639341,0.0002118781],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002084619,0.9931091,0.0001757002,0.0001144199,0.0001030552,0.003437533,0.0001002949,0.0001178544,0.0007574394],"genre_scores_gemma":[0.005108368,0.9889459,0.0009075662,0.000008519805,0.0006780793,0.001235203,0.0002677823,0.0000553351,0.002793226],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8759919,"threshold_uncertainty_score":0.9999483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1042210286877916,"score_gpt":0.413893231678394,"score_spread":0.3096722029906024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}