{"id":"W2074064949","doi":"10.1371/journal.pone.0039214","title":"IL-17A Synergizes with IFN-γ to Upregulate iNOS and NO Production and Inhibit Chlamydial Growth","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Tianjin Science and Technology Committee; National Natural Science Foundation of China","keywords":"Nitric oxide synthase; Proinflammatory cytokine; Cytokine; Nitric oxide; Interferon gamma; Biology; In vivo; Microbiology; Macrophage; In vitro; Chemistry; Chlamydophila pneumoniae; Immunology; Molecular biology; Chlamydia; Inflammation; Chlamydiaceae; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003285952,0.0001443275,0.0002162958,0.0001689861,0.0002023026,0.00002268319,0.00005564126,0.0001134422,0.0001182337],"category_scores_gemma":[0.0005707442,0.0001174651,0.00001372321,0.0001983901,0.0002777152,0.0003370367,0.0001006985,0.0002741012,0.0005708803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003340165,"about_ca_system_score_gemma":0.00002480974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008555515,"about_ca_topic_score_gemma":0.00001764631,"domain_scores_codex":[0.9989133,0.0001286519,0.0001389023,0.0003779026,0.00006843316,0.0003727678],"domain_scores_gemma":[0.9993369,0.00006013101,0.0000431273,0.0002614486,0.0002382654,0.00006015621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003912187,0.0009966213,0.07396333,0.00008077457,0.0003778574,5.443332e-7,0.0006249522,6.799406e-7,0.9217066,0.0002294067,0.0006668339,0.0009611519],"study_design_scores_gemma":[0.0004547723,0.0005596144,0.1875098,0.00009833918,0.0000952113,0.00008211961,0.00005456234,5.106495e-7,0.8093449,0.0000440956,0.001563912,0.0001921279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965833,0.0005826296,0.000009228242,0.0006666665,0.0001532084,0.0006294347,0.000008830947,0.00007617254,0.001290564],"genre_scores_gemma":[0.9946401,0.00014422,0.0003829795,0.00003004266,0.0002641574,0.00009940958,0.00001266323,0.00002136404,0.00440512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1135465,"threshold_uncertainty_score":0.7337702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02568860274335792,"score_gpt":0.2295802792292613,"score_spread":0.2038916764859033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}