{"id":"W2074079209","doi":"10.1016/j.ydbio.2006.09.053","title":"The C. elegans anaphase promoting complex and MBK-2/DYRK kinase act redundantly with CUL-3/MEL-26 ubiquitin ligase to degrade MEI-1 microtubule-severing activity after meiosis","year":2006,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Ubiquitin ligase; Mitosis; Ectopic expression; Cell biology; Anaphase; Spindle apparatus; Anaphase-promoting complex; Ubiquitin; Molecular biology; Cell cycle; Genetics; Cell division; Cell; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000277202,0.000378413,0.000276883,0.00006978956,0.0004424136,0.00009467473,0.0002841394,0.0001880237,0.00001729861],"category_scores_gemma":[0.0000396226,0.0002921391,0.00006305303,0.0001409819,0.0002927549,0.00001047999,0.0003269794,0.0001651191,0.00001342931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006387107,"about_ca_system_score_gemma":0.0001210555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002227283,"about_ca_topic_score_gemma":0.00148871,"domain_scores_codex":[0.9980801,0.0001269101,0.0003121189,0.0007030191,0.0001195849,0.00065829],"domain_scores_gemma":[0.999311,0.00003128441,0.0001202675,0.0003012602,0.00006102204,0.0001751935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002921454,0.0001052764,0.02733768,0.00002663154,0.00008261259,0.00002489872,0.0005057414,0.000008374601,0.9659675,0.00001630886,0.0004261409,0.005206707],"study_design_scores_gemma":[0.000790954,0.0004744152,0.05105243,0.00003043947,0.00003081893,0.0001760822,0.0002265093,0.00003951255,0.9174966,0.00004219835,0.02908937,0.0005506696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965507,0.0004425101,0.001507086,0.0006048786,0.0000951293,0.0004893859,0.00005504219,0.00004403657,0.0002112332],"genre_scores_gemma":[0.990378,0.00008288524,0.008396497,0.00056581,0.0001433657,0.00009406305,0.0001198332,0.00005727087,0.0001622776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04847088,"threshold_uncertainty_score":0.9999531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00753428364657611,"score_gpt":0.2220376711628099,"score_spread":0.2145033875162338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}