{"id":"W2074094083","doi":"10.3410/b1-93","title":"Aberrant mRNA transcripts and nonsense-mediated decay","year":2009,"lang":"en","type":"article","venue":"F1000 Biology Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Nonsense-mediated decay; Nonsense; nobody; Biology; Messenger RNA; Arabidopsis; Arabidopsis thaliana; Genetics; Cell biology; Computational biology; Gene; RNA; Computer science; Mutant; RNA splicing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003005103,0.0001571256,0.000193574,0.00005707104,0.00009684281,0.00001597565,0.00007724356,0.0002422483,0.00002168797],"category_scores_gemma":[0.0001085914,0.0001302064,0.00006802363,0.0000734286,0.0001384179,0.00000302998,0.00002882346,0.0001253466,0.00000650577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007013152,"about_ca_system_score_gemma":0.00007653606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004368385,"about_ca_topic_score_gemma":0.00003741575,"domain_scores_codex":[0.9987172,0.00007160865,0.0002825951,0.0004567241,0.00007712046,0.0003947494],"domain_scores_gemma":[0.9993218,0.00001571476,0.00008029099,0.0003408843,0.00006148015,0.0001798837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007477105,0.00003406552,0.01514532,0.000003668353,0.00002980414,0.0002393421,0.00002077103,0.000001022317,0.9781448,0.00003098009,0.001828097,0.00444742],"study_design_scores_gemma":[0.001372826,0.002370241,0.1403314,0.00003520913,0.00004037071,0.004615926,0.00005833888,0.00008691088,0.6786352,0.0007340725,0.1709682,0.0007512416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945104,0.001958321,0.0002045139,0.0007801648,0.000142712,0.000174302,0.000007962385,0.00002681043,0.00219484],"genre_scores_gemma":[0.9967576,0.0004696354,0.000189395,0.0006965493,0.0001294687,0.000008257778,0.0001738458,0.00001169813,0.001563537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2995096,"threshold_uncertainty_score":0.5309662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0111531023854271,"score_gpt":0.2715258978743598,"score_spread":0.2603727954889327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}