{"id":"W2074161808","doi":"10.1530/erc-13-0450","title":"COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion","year":2014,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Downregulation and upregulation; Epidermal growth factor; PI3K/AKT/mTOR pathway; Cancer research; Ovarian cancer; CREB; Protein kinase B; Cell growth; Cadherin; Signal transduction; Biology; Cancer cell; Cell biology; Cell; Cancer; Cell culture; Internal medicine; Medicine; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003393133,0.000384556,0.0005895159,0.0001238695,0.0002057187,0.00002922236,0.0001285864,0.0002180651,0.001899517],"category_scores_gemma":[0.00006575078,0.0003241667,0.0001156525,0.0002029534,0.00007180841,0.000149622,0.0001058769,0.0006671583,0.00009592385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003275651,"about_ca_system_score_gemma":0.0001849224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003133207,"about_ca_topic_score_gemma":0.0009062625,"domain_scores_codex":[0.997662,0.0001378829,0.0004921234,0.0005787666,0.0004958962,0.000633338],"domain_scores_gemma":[0.9986541,0.00008373765,0.0002139974,0.000444955,0.000114402,0.0004888435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004820903,0.0003017035,0.0864225,0.001082132,0.0005008085,0.0006855285,0.001536554,0.00007212366,0.8519611,0.001247719,0.00802045,0.04768734],"study_design_scores_gemma":[0.0312485,0.001879845,0.1946549,0.001661927,0.001381069,0.000384496,0.000244748,0.002591964,0.6326787,0.0004559395,0.1309215,0.001896362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839329,0.003111207,0.000007215828,0.0007831567,0.001377319,0.0006551591,0.000009526267,0.0001879903,0.009935528],"genre_scores_gemma":[0.9921669,0.002053532,0.00003758164,0.0004960365,0.0008508693,0.0002092703,0.00003023211,0.00009355415,0.004062004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2192824,"threshold_uncertainty_score":0.999921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233573774889245,"score_gpt":0.2800495222313698,"score_spread":0.2677137844824773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}