{"id":"W2074171805","doi":"10.1111/j.1749-6632.2002.tb02964.x","title":"Role of Donor MHC Class III Genes in the Destruction of Transplanted Islets in NOD Mice","year":2002,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Western University","funders":"","keywords":"MHC class I; Islet; NOD mice; Nod; Major histocompatibility complex; MHC class II; Biology; Immunology; CD74; Transplantation; Immune system; CD1; Cancer research; Gene; CD8; Medicine; Genetics; Endocrinology; Internal medicine; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000703842,0.0004907798,0.0004859707,0.0004677896,0.0001951081,0.0006735727,0.0003785821,0.000556629,0.001292813],"category_scores_gemma":[0.0004061402,0.0002512946,0.0003370813,0.0001995068,0.0004900346,0.0003133047,0.0003271318,0.001315773,0.0004826139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002541559,"about_ca_system_score_gemma":0.0002156317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000147021,"about_ca_topic_score_gemma":0.0002342763,"domain_scores_codex":[0.9995196,0.0001073566,0.00006085097,0.00009531878,0.0001137933,0.0001031156],"domain_scores_gemma":[0.9993417,0.0001040396,0.0002041462,0.0001046062,0.00002222711,0.000223241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006700692,0.0001837096,0.00099918,0.00005736656,0.000008426641,0.0002515806,0.00003576307,0.00005847124,0.99525,0.0002726073,0.00002765924,0.002185228],"study_design_scores_gemma":[0.0001868073,0.001648679,0.01424103,0.00005628547,0.00008883138,0.002687032,0.0001286453,0.001034549,0.9771715,0.0003908577,0.002353281,0.00001240523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928887,0.001826168,0.002747592,0.0001230681,0.0000430743,0.00003957114,0.0001927127,0.0001141753,0.002024927],"genre_scores_gemma":[0.9939977,0.001187436,0.002239237,0.0001204027,0.00002155743,0.00008064036,0.0002604123,0.00007423761,0.002018466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292813,"threshold_uncertainty_score":0.004324913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07120711360806344,"score_gpt":0.3023559405895047,"score_spread":0.2311488269814412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}