{"id":"W2074206082","doi":"10.1021/bc990171x","title":"Fluorescent-Labeled Poly(ethylene glycol) Lipid Conjugates With Distal Cationic Headgroups","year":2000,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Inimex Pharmaceuticals (Canada); University of British Columbia","funders":"","keywords":"Chemistry; Ethylene glycol; Moiety; Fluorescence; Cationic polymerization; Liposome; PEG ratio; Bilayer; Conjugate; Combinatorial chemistry; Lysine; Lipid bilayer; Membrane; Phosphatidylethanolamine; Biophysics; Polymer chemistry; Organic chemistry; Amino acid; Biochemistry; Phospholipid; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000919162,0.0003763491,0.0002572662,0.00001977575,0.0001634012,0.00008950392,0.0003947908,0.0002750439,0.001199969],"category_scores_gemma":[0.00001945406,0.0003352804,0.0001238398,0.0001225301,0.0002517021,0.00001316814,0.0000733156,0.0001706601,0.0002075349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003934846,"about_ca_system_score_gemma":0.0001631026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007542899,"about_ca_topic_score_gemma":0.0000326752,"domain_scores_codex":[0.9982135,0.00003025323,0.0003343878,0.0007002298,0.0002047525,0.0005168968],"domain_scores_gemma":[0.9988497,0.000009797569,0.0001032888,0.0006836985,0.0001308834,0.0002225913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005635243,0.0001430371,0.001185219,0.00006240418,0.0001119936,0.0000172423,0.00003547725,0.000009626305,0.9920675,0.00000734949,0.002254932,0.003541741],"study_design_scores_gemma":[0.001212498,0.0002994448,0.0003920179,0.00005807789,0.00003680157,0.00009539666,0.00007563653,0.00002906554,0.961311,0.000016869,0.03599158,0.0004816496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925138,0.001481252,0.00004200051,0.0002708002,0.00007496432,0.0002330955,0.0001011378,0.0000554232,0.005227486],"genre_scores_gemma":[0.9876058,0.000688959,0.0001966955,0.0003776606,0.0005990157,0.00007814033,0.0008783974,0.00005303788,0.00952229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03373665,"threshold_uncertainty_score":0.9999099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00477736407845158,"score_gpt":0.2050141834028149,"score_spread":0.2002368193243633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}