{"id":"W2074206082","doi":"10.1021/bc990171x","title":"Fluorescent-Labeled Poly(ethylene glycol) Lipid Conjugates With Distal Cationic Headgroups","year":2000,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Inimex Pharmaceuticals (Canada); University of British Columbia","funders":"","keywords":"Chemistry; Ethylene glycol; Moiety; Fluorescence; Cationic polymerization; Liposome; PEG ratio; Bilayer; Conjugate; Combinatorial chemistry; Lysine; Lipid bilayer; Membrane; Phosphatidylethanolamine; Biophysics; Polymer chemistry; Organic chemistry; Amino acid; Biochemistry; Phospholipid; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519012,0.0005715044,0.000253014,0.0002061912,0.0001333998,0.0002697905,0.0003294538,0.0004228493,0.001174985],"category_scores_gemma":[0.0001827821,0.0002206918,0.0001643481,0.0001845192,0.0002752689,0.0004424869,0.0002606547,0.0005830437,0.001134183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004391992,"about_ca_system_score_gemma":0.0001616457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002193201,"about_ca_topic_score_gemma":0.0003334351,"domain_scores_codex":[0.9998984,0.00001434812,0.000009545204,0.00002702493,0.00003340305,0.00001723685],"domain_scores_gemma":[0.9998877,0.00001818109,0.00003146403,0.00001249265,0.00001749579,0.00003265993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004328903,0.00001155244,0.00003821181,0.00003307372,0.000001868666,0.00003838259,0.000005311215,0.0001242954,0.9970795,0.0001982579,0.00005383294,0.002372416],"study_design_scores_gemma":[0.00001482042,0.0001040411,0.0002407362,0.000003139726,0.000006722053,0.0002250998,0.000002252501,0.0005361647,0.9913953,0.00006842235,0.007397979,0.000005456304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.819983,0.009297894,0.1590269,0.0006139803,0.0002906238,0.0002826599,0.0008359543,0.00123764,0.008431424],"genre_scores_gemma":[0.8853948,0.005424359,0.08911461,0.0004183305,0.00009464355,0.0003009452,0.001228247,0.0001376488,0.01788635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001174985,"threshold_uncertainty_score":0.003930748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00477736407845158,"score_gpt":0.2050141834028149,"score_spread":0.2002368193243633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}