{"id":"W2074247847","doi":"10.1089/104454900750019344","title":"Modulation of the Far-Upstream Enhancer of the Rat α-Fetoprotein Gene by Members of the RORα, Rev-erbα, and Rev-erbβ Groups of Monomeric Orphan Nuclear Receptors","year":2000,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"Fondation pour la Recherche Médicale","keywords":"Enhancer; Biology; Nuclear receptor; Orphan receptor; Molecular biology; Receptor; Regulation of gene expression; Gene expression; Transcription factor; Gene; Chromatin; Hepatocyte nuclear factor 4; Transfection; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001428604,0.0003179583,0.0001674952,0.0001430096,0.00007260431,0.0001547731,0.0001272657,0.0001417948,0.0009212493],"category_scores_gemma":[0.0001735764,0.0001269311,0.0002118316,0.00006746133,0.0001978106,0.0001222178,0.0001466648,0.0003356439,0.0003041707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001494348,"about_ca_system_score_gemma":0.0001019261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002314038,"about_ca_topic_score_gemma":0.0003780916,"domain_scores_codex":[0.9998252,0.00005149702,0.00001251425,0.00003570368,0.00002982733,0.00004530148],"domain_scores_gemma":[0.9998995,0.0000249552,0.00002924194,0.0000125459,0.00001072559,0.0000230537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005614983,0.000008136446,0.00007353397,0.00000907694,0.000001613387,0.00001491627,0.00000755468,0.00001843463,0.9993481,0.00004486502,0.000004306107,0.0004132704],"study_design_scores_gemma":[0.00002338762,0.0004877642,0.005243736,0.000007992076,0.00001836447,0.000220797,0.00004302125,0.000788108,0.9916329,0.0000458947,0.001483279,0.000004720112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960513,0.001174773,0.001649237,0.0000423017,0.00001694425,0.00001296766,0.00006105315,0.0000258379,0.0009655964],"genre_scores_gemma":[0.9962057,0.0005555945,0.001450108,0.00003064398,0.000007749356,0.00002122282,0.0001723904,0.000007825569,0.00154878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009212493,"threshold_uncertainty_score":0.003081858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006652500764045711,"score_gpt":0.1917383291990817,"score_spread":0.185085828435036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}