{"id":"W2074274213","doi":"10.1007/s00702-011-0672-z","title":"Neurocognitive-genetic and neuroimaging-genetic research paradigms in schizophrenia and bipolar disorder","year":2011,"lang":"en","type":"review","venue":"Journal of Neural Transmission","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Ministry of Education, India; Ministry of Earth Sciences; National University of Singapore","keywords":"Neurocognitive; Neuroimaging; Psychology; Neuroscience; Schizophrenia (object-oriented programming); Imaging genetics; rs4680; Bipolar disorder; Catechol-O-methyl transferase; Neuroplasticity; Cognition; Psychiatry; Genetics; Genotype; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00113156,0.001106125,0.001891571,0.002444976,0.0002843333,0.001102817,0.001112873,0.001377094,0.002179448],"category_scores_gemma":[0.001213465,0.0003279405,0.0006249305,0.002487095,0.0008694171,0.001561383,0.0007745178,0.001847705,0.0007508722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000876423,"about_ca_system_score_gemma":0.001539984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002516226,"about_ca_topic_score_gemma":0.007956866,"domain_scores_codex":[0.999808,0.0000471651,0.00004192303,0.00003286355,0.00005565543,0.00001437346],"domain_scores_gemma":[0.999386,0.0004080041,0.00006854655,0.00001194015,0.00009180925,0.0000337143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001394772,0.0001275797,0.0004010565,0.01658472,0.0001912926,0.0005496769,0.0000780405,0.0003213999,0.001101027,0.004751777,0.01849658,0.9572573],"study_design_scores_gemma":[0.0001347385,0.0002397803,0.004839193,0.01783001,0.0008660261,0.00586145,0.0003338759,0.0003136736,0.0007830246,0.01299974,0.9557142,0.00008423415],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005697188,0.9994141,0.00004290852,0.0001453386,0.00006065453,0.000001534297,0.000004403455,0.000001371341,0.0002727555],"genre_scores_gemma":[0.0004665981,0.9989609,0.0001584194,0.0001488126,0.0001180112,0.000002949386,0.000008800815,3.685321e-7,0.0001350991],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002516226,"threshold_uncertainty_score":0.007290959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09934562837218225,"score_gpt":0.3762940442801324,"score_spread":0.2769484159079501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}