{"id":"W2074276586","doi":"10.1152/ajpheart.01304.2004","title":"Modification of sarcolemmal Na+-K+-ATPase and Na+/Ca2+exchanger expression in heart failure by blockade of renin-angiotensin system","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Internal medicine; Heart failure; Losartan; Endocrinology; Chemistry; Renin–angiotensin system; Plasma renin activity; Sodium–hydrogen antiporter; Enalapril; Angiotensin II; Angiotensin-converting enzyme; Sodium; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001217303,0.0002506629,0.0003125496,0.0001247936,0.000100931,0.0001806708,0.0001396836,0.0002538038,0.0006810841],"category_scores_gemma":[0.0000958936,0.0001596184,0.0001989172,0.00005969315,0.0002051017,0.0002297193,0.00009604049,0.0003793482,0.0001136212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001138216,"about_ca_system_score_gemma":0.0001294958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002808622,"about_ca_topic_score_gemma":0.0004515133,"domain_scores_codex":[0.999935,0.00001016338,0.000005983855,0.00001386208,0.00001088586,0.00002411965],"domain_scores_gemma":[0.9999117,0.000008232828,0.00003430826,0.000005871646,0.00001008799,0.00002970761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004766557,0.00004014325,0.0005726319,0.00003250574,0.00000714072,0.00003492812,0.0000120375,0.00001681381,0.9979691,0.00002619316,0.00001194415,0.0007998581],"study_design_scores_gemma":[0.0002000577,0.003464402,0.1353232,0.00001688608,0.0001059359,0.0005545856,0.000138243,0.001527734,0.8570129,0.0001605277,0.001482093,0.00001348846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981759,0.001127971,0.0004027379,0.00004143173,0.00001313767,0.000007444029,0.00003610209,0.00001643445,0.0001789961],"genre_scores_gemma":[0.9980451,0.0007601315,0.0004256031,0.0000275876,0.00001378797,0.00002174589,0.00008537202,0.000004325889,0.0006163098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006810841,"threshold_uncertainty_score":0.002278388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008555099283054216,"score_gpt":0.2380109648050109,"score_spread":0.2294558655219567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}