{"id":"W2074278201","doi":"10.1074/jbc.m200268200","title":"A Novel Family of Calmodulin-binding Transcription Activators in Multicellular Organisms","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":343,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences","keywords":"Biology; Transcription factor; Calmodulin; Repressor lexA; Calmodulin-binding proteins; Ankyrin repeat; DNA-binding protein; DNA-binding domain; Genetics; Transcription (linguistics); Cell biology; cDNA library; Gene; Complementary DNA; Molecular biology; Biochemistry; Repressor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003214331,0.0001461863,0.0002843359,0.00003232853,0.00002415775,0.000008007513,0.0002412131,0.0003433138,0.0001284587],"category_scores_gemma":[0.0002246197,0.0001115911,0.0001745595,0.0001019876,0.00005870477,0.000005990732,0.00002995703,0.0001851358,0.000002054479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002345285,"about_ca_system_score_gemma":0.00002012658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004257514,"about_ca_topic_score_gemma":3.26177e-7,"domain_scores_codex":[0.9989398,0.00004265249,0.0004986048,0.000181904,0.0001519309,0.0001851062],"domain_scores_gemma":[0.9993451,0.00002359315,0.000323804,0.0001423143,0.00007921028,0.00008597365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001159456,0.0002355525,0.001023443,0.00002604902,0.0000324072,0.00001253781,0.00003917783,0.00002744394,0.9974418,0.000002019633,0.00003124309,0.001012398],"study_design_scores_gemma":[0.0007280443,0.0002487917,0.0008633108,0.00005160319,0.00001268178,0.00007514157,0.0002186457,0.00003494674,0.9970881,0.00003244998,0.000514494,0.0001317774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951108,0.0009835361,0.0034404,0.00005155609,0.00007524423,0.00006390995,0.000009870276,0.000003080171,0.0002616734],"genre_scores_gemma":[0.9966947,0.0002684514,0.002717746,0.00003612009,0.0001542782,0.000002382559,0.000005978573,0.0000109754,0.0001093272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001584011,"threshold_uncertainty_score":0.4550555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03469552388204558,"score_gpt":0.2322781240583976,"score_spread":0.197582600176352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}