{"id":"W2074297244","doi":"10.1074/jbc.m002830200","title":"Endotoxin-induced Renal Inflammatory Response","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Arthritis Society","keywords":"Acute-phase protein; Oncostatin M; Renin–angiotensin system; Proinflammatory cytokine; Inflammation; Kidney; Haptoglobin; Endocrinology; Internal medicine; Medicine; Blood pressure; Interleukin 6","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002681633,0.0003285846,0.0003029971,0.0002341997,0.000129922,0.0001942198,0.00009082032,0.0002057693,0.002263307],"category_scores_gemma":[0.0002567799,0.00008834588,0.0002583801,0.0001150492,0.0001930254,0.0001268479,0.0002527876,0.0004814232,0.0003612515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001757664,"about_ca_system_score_gemma":0.0002160034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001456805,"about_ca_topic_score_gemma":0.0001466901,"domain_scores_codex":[0.9996771,0.00008904225,0.0000371743,0.00003806055,0.00008619035,0.00007252482],"domain_scores_gemma":[0.999803,0.00002562847,0.00005764922,0.00003035601,0.00003027379,0.00005302059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004135473,0.00007663207,0.0007076029,0.000104786,0.000008806541,0.0002737668,0.00002119538,0.00004417294,0.9945711,0.000192896,0.00007384274,0.003511558],"study_design_scores_gemma":[0.000137304,0.003072417,0.03950273,0.0000296529,0.00006042608,0.00358097,0.00008927874,0.001115726,0.945861,0.000339763,0.006193735,0.00001695602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856162,0.003495907,0.006278114,0.0001372125,0.00009233927,0.0001568264,0.0003033989,0.000181787,0.003738214],"genre_scores_gemma":[0.994445,0.001126166,0.00172977,0.0001309705,0.00003463968,0.00006251402,0.0002706065,0.000008317551,0.002191995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002263307,"threshold_uncertainty_score":0.007571518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015875370871243,"score_gpt":0.2704073913610718,"score_spread":0.2502486376523594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}