{"id":"W2074336937","doi":"10.1007/s00244-004-0049-5","title":"Biological Activity and Physicochemical Parameters of Marine Halogenated Natural Products 2,3,3′,4,4′,5,5′-Heptachloro-1′-Methyl-1,2′-Bipyrrole and2,4,6-Tribromoanisole","year":2004,"lang":"en","type":"article","venue":"Archives of Environmental Contamination and Toxicology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Fisheries and Oceans Canada","funders":"Woods Hole Oceanographic Institution","keywords":"Chemistry; Ligand (biochemistry); Potency; Bioassay; Solubility; Sulforhodamine B; Biological activity; IC50; Cytotoxicity; In vitro; Stereochemistry; Chromatography; Nuclear chemistry; Environmental chemistry; Receptor; Organic chemistry; Biochemistry; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001044624,0.0002071627,0.00008716355,0.0001913162,0.000098726,0.0001548905,0.00007859025,0.0001720634,0.001114406],"category_scores_gemma":[0.0001857965,0.0001003661,0.0001959034,0.0001355976,0.0001574286,0.0001173593,0.00007829194,0.0001715125,0.0002252943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001587629,"about_ca_system_score_gemma":0.0001814724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001965284,"about_ca_topic_score_gemma":0.0017047,"domain_scores_codex":[0.9999326,0.00001078217,0.000005046892,0.00001506761,0.00001949377,0.00001689544],"domain_scores_gemma":[0.9998708,0.00002756788,0.00002737872,0.00001090474,0.00003111874,0.00003222478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002364508,0.0000177947,0.001997484,0.00002049672,0.000008148102,0.00003582055,0.00002292559,0.0001063825,0.9964095,0.000025094,0.00002378563,0.001096044],"study_design_scores_gemma":[0.000009964187,0.0008690103,0.04859449,0.00000341515,0.00002286776,0.0001863681,0.00007879041,0.000520761,0.9488535,0.00004437776,0.0008077984,0.000008567479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998687,0.0004989692,0.0001644939,0.0000116484,0.000004982574,0.00000307891,0.0002224037,0.000005192666,0.0004023117],"genre_scores_gemma":[0.9974474,0.0003166696,0.000152848,0.00001508404,0.000005231012,0.000007640858,0.0005890877,0.000002821588,0.001463245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001965284,"threshold_uncertainty_score":0.003907681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007478913756317864,"score_gpt":0.2103735096221424,"score_spread":0.2028945958658246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}