{"id":"W2074356915","doi":"10.1074/jbc.m311830200","title":"CYP2U1, a Novel Human Thymus- and Brain-specific Cytochrome P450, Catalyzes ω- and (ω-1)-Hydroxylation of Fatty Acids","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Arachidonic acid; Biochemistry; Hydroxylation; Cytochrome P450; Fatty acid; Biology; Lauric acid; Hydroxyeicosatetraenoic acid; Epoxyeicosatrienoic acid; Chemistry; Metabolism; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349772,0.000545568,0.0003195796,0.0004143043,0.0003133042,0.0004317718,0.0001683146,0.0003635565,0.001031533],"category_scores_gemma":[0.000202631,0.0001613364,0.0002930458,0.0004393912,0.0001797411,0.0001906424,0.0001798921,0.0003718593,0.0006347144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002850561,"about_ca_system_score_gemma":0.0001891479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009135285,"about_ca_topic_score_gemma":0.0009293738,"domain_scores_codex":[0.9998322,0.0000311581,0.000007671862,0.00006709905,0.00003323247,0.00002873486],"domain_scores_gemma":[0.9999195,0.00001643498,0.0000242516,0.000006744633,0.00001510998,0.0000178917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003372723,0.0000846502,0.01290646,0.0002279928,0.00008479038,0.001066918,0.0001093875,0.0003606441,0.9183026,0.0006732308,0.001340848,0.0645051],"study_design_scores_gemma":[0.00008714129,0.0007646121,0.1048338,0.00003810375,0.0001316729,0.01037179,0.0001255256,0.004530667,0.826551,0.0006138612,0.05191321,0.00003879193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9014691,0.04420428,0.04371486,0.0009050145,0.0002120974,0.0002248133,0.002461333,0.0008456892,0.005962808],"genre_scores_gemma":[0.9693563,0.008818099,0.009710619,0.0001397141,0.0001677148,0.00008117337,0.00322567,0.0000491168,0.008451586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031533,"threshold_uncertainty_score":0.003450871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02529272194990885,"score_gpt":0.2743728720009532,"score_spread":0.2490801500510444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}