{"id":"W2074377037","doi":"10.1016/j.ydbio.2003.07.002","title":"The catalytic domain of xPAK1 is sufficient to induce myosin II dependent in vivo cell fragmentation independently of other apoptotic events","year":2003,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"National Cancer Institute","keywords":"Biology; Cell biology; Apoptosis; Myosin; Cytoskeleton; Phosphorylation; PAK1; Fragmentation (computing); Actin; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003575087,0.0001359557,0.0001503586,0.00007142451,0.00007995474,0.000003699807,0.0001598849,0.0001608462,0.00005419868],"category_scores_gemma":[0.00001959338,0.0001071692,0.00004630506,0.0001301803,0.00004842474,0.000002994651,0.0001126038,0.00005547672,0.000007306953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005982291,"about_ca_system_score_gemma":0.0001063092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007590787,"about_ca_topic_score_gemma":0.0001273327,"domain_scores_codex":[0.99888,0.00009236707,0.0003916842,0.0002809729,0.000129755,0.0002251988],"domain_scores_gemma":[0.9995814,0.00001448031,0.0001496872,0.0001629047,0.00004534881,0.0000461674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005686597,0.0001564486,0.007760931,0.00001166368,0.00002395608,4.177744e-7,0.0006991994,0.0000523163,0.9900533,0.0004582143,0.00005772652,0.000668958],"study_design_scores_gemma":[0.0006565839,0.0002553278,0.005085623,0.00001203209,0.000005745083,0.000005929502,0.000761651,0.000004721563,0.989555,0.0002831509,0.003243749,0.00013048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975796,0.0001762439,0.0008761149,0.00004176172,0.0001989115,0.0003551952,0.00002409988,0.000002266094,0.0007457577],"genre_scores_gemma":[0.9976944,0.00004139346,0.001437804,0.0001420451,0.00001043252,0.00002399036,0.00004309245,0.00001244513,0.0005944096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003186023,"threshold_uncertainty_score":0.4370233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007529102786619664,"score_gpt":0.2353883324360334,"score_spread":0.2278592296494137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}