{"id":"W2074389485","doi":"10.1159/000235312","title":"CI-959, a New, Potential Antiallergic Drug, Inhibits Mediator Release from Lung and Contractions of Human Airways in vitro","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Histamine; Leukotriene; Thromboxane; Guinea pig; Endocrinology; Chemistry; Arachidonic acid; Internal medicine; Leukotriene C4; Leukotriene D4; In vitro; Bronchoconstriction; Pharmacology; Medicine; Biochemistry; Asthma; Platelet; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002360084,0.0006375891,0.0004129091,0.0004263558,0.0001392921,0.0003642698,0.0005682792,0.0003644519,0.002146021],"category_scores_gemma":[0.0003476448,0.0002324066,0.0002768531,0.0002514724,0.0002240414,0.0001969954,0.0002083029,0.0006634596,0.001061586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002503034,"about_ca_system_score_gemma":0.0002951222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007698008,"about_ca_topic_score_gemma":0.001401457,"domain_scores_codex":[0.9997109,0.0000597254,0.00003484845,0.00004984608,0.00009189008,0.00005287009],"domain_scores_gemma":[0.9998884,0.00003285065,0.00002830648,0.000009730028,0.000009025836,0.00003167283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006791593,0.0002680563,0.0005612519,0.0003324452,0.00005176472,0.0001700355,0.00002714165,0.0001131943,0.9697912,0.0001634851,0.0006453655,0.0271968],"study_design_scores_gemma":[0.000590496,0.009448607,0.02461359,0.00007246123,0.0001736096,0.003410036,0.00004426848,0.0009516273,0.9354092,0.0000763645,0.02518392,0.00002570553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8572862,0.1206612,0.006140991,0.0004536187,0.0002652894,0.0002208305,0.001242185,0.0005075925,0.01322208],"genre_scores_gemma":[0.9533604,0.03400493,0.003493428,0.0002561412,0.0001230511,0.0001218929,0.002625801,0.00004065448,0.005973662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002146021,"threshold_uncertainty_score":0.007179201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004060232121545016,"score_gpt":0.2321146624103255,"score_spread":0.2280544302887805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}