{"id":"W2074417648","doi":"10.1074/jbc.m209709200","title":"Mitochondrial Functional State in Clonal Pancreatic β-Cells Exposed to Free Fatty Acids","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island; University of Toronto","funders":"","keywords":"Mitochondrion; Oxidative phosphorylation; Reactive oxygen species; Internal medicine; Insulin; Endocrinology; Respiratory chain; Biology; Uncoupling protein; Cellular respiration; Fatty acid; Secretion; Superoxide; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001842826,0.00022997,0.0003039484,0.0001447203,0.0001376875,0.000307255,0.0001684947,0.0002614188,0.0007660405],"category_scores_gemma":[0.000173859,0.0001164455,0.0002683979,0.0002180287,0.000122413,0.0002541872,0.0002375028,0.0005124559,0.0002292978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001279073,"about_ca_system_score_gemma":0.00008240949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004130939,"about_ca_topic_score_gemma":0.0003735306,"domain_scores_codex":[0.9997836,0.00002864769,0.00003421764,0.00006088133,0.00005727945,0.00003535082],"domain_scores_gemma":[0.9998277,0.00002628414,0.00004283815,0.00003263925,0.00003493335,0.00003555508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001562151,0.00002148085,0.0006395909,0.00001793968,0.000005684043,0.00005760115,0.00003125386,0.00001727512,0.9984731,0.00001581518,0.00001006845,0.0005539164],"study_design_scores_gemma":[0.00001550489,0.001178938,0.03936115,0.00001141989,0.00004395442,0.0006056225,0.0002227029,0.0005517793,0.9561396,0.00005434748,0.001804724,0.00001030097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963493,0.001581641,0.001159849,0.00004340043,0.00003187574,0.00001189935,0.000345232,0.00001397132,0.0004627795],"genre_scores_gemma":[0.9953361,0.001108256,0.001232291,0.00005827271,0.00001648827,0.00003580593,0.001182883,0.00001025921,0.001019569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007660405,"threshold_uncertainty_score":0.002562642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02978957024485846,"score_gpt":0.2471350796641352,"score_spread":0.2173455094192767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}