{"id":"W2074428618","doi":"10.1074/jbc.m112.402727","title":"DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Cluster (Canada)","funders":"Koning Boudewijnstichting; Cancer Research UK","keywords":"Cell biology; Histone acetyltransferase; Acetylation; Cytoplasm; Protein subunit; Biology; Acetyltransferase; Melanoma; Yeast; Function (biology); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006606846,0.0003991969,0.0001295469,0.0002115257,0.0001800179,0.0002259633,0.0001623814,0.0002259325,0.001845059],"category_scores_gemma":[0.00007004001,0.00009338908,0.0002667547,0.0001121955,0.0001640293,0.0001450768,0.000239402,0.0003827532,0.0005148928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684396,"about_ca_system_score_gemma":0.0001462285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008499342,"about_ca_topic_score_gemma":0.00106942,"domain_scores_codex":[0.9999075,0.000008701254,0.000007907772,0.00002525797,0.0000251776,0.00002554231],"domain_scores_gemma":[0.999943,0.000004411151,0.00001798575,0.000004615323,0.000005799692,0.00002408125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001120848,0.00001409307,0.0008418729,0.00002629956,0.000006495713,0.0001910086,0.000009466487,0.0001183238,0.9970216,0.0001372599,0.00007400795,0.001447411],"study_design_scores_gemma":[0.00001535397,0.0001088287,0.0359639,0.000006928395,0.00002022727,0.0008709636,0.00006564331,0.002425788,0.9565341,0.00009854745,0.00388366,0.000006068591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947867,0.001266882,0.00193449,0.00007762093,0.00002187564,0.00001338746,0.00065466,0.00007096819,0.001173409],"genre_scores_gemma":[0.9952872,0.0004560314,0.0009091428,0.00003945462,0.000004059375,0.0000132179,0.0007529178,0.00001196387,0.002526111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001845059,"threshold_uncertainty_score":0.006172359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567922812429371,"score_gpt":0.2595065474841001,"score_spread":0.2438273193598064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}