{"id":"W2074478540","doi":"10.1074/jbc.m510441200","title":"Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-β1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"Vancouver Coastal Health Research Institute","keywords":"Phosphorylation; Cell biology; Fibroblast; Extracellular; MAPK/ERK pathway; Fibroblast growth factor; Transforming growth factor; p38 mitogen-activated protein kinases; Chemistry; Growth factor; Cancer research; Biology; Biochemistry; In vitro; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001360739,0.0002144304,0.0005814711,0.00006121722,0.00003402167,0.000008266187,0.00009163234,0.0003043882,0.0001626262],"category_scores_gemma":[0.0001931489,0.0001599681,0.0002033713,0.0000988102,0.0001966216,0.0001934765,0.00003135762,0.0002932755,3.066658e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005498465,"about_ca_system_score_gemma":0.00007987555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001238161,"about_ca_topic_score_gemma":2.009544e-7,"domain_scores_codex":[0.9983577,0.00003899524,0.0009200133,0.0002080461,0.0002993713,0.000175834],"domain_scores_gemma":[0.998621,0.00009101268,0.0006351738,0.00008996212,0.0003400383,0.0002228159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003917406,0.0003388438,0.005061453,0.0009549978,0.00008350507,0.00001974429,0.0002350232,8.894112e-7,0.9882042,0.000005556018,0.00004294324,0.001135385],"study_design_scores_gemma":[0.00117015,0.002413344,0.006855701,0.001006726,0.00009036093,0.0001844406,0.0001800176,0.0005105968,0.9873737,0.00003857339,0.00003019852,0.0001462509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971772,0.001712454,0.0002844718,0.000278521,0.00002447677,0.0001639778,0.0002445502,0.000007961185,0.0001064336],"genre_scores_gemma":[0.9989401,0.0005930109,0.0001897974,0.00002700148,0.0001590358,0.000001794987,0.00005742896,0.00001256648,0.00001930438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002747255,"threshold_uncertainty_score":0.6523311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01342145138420823,"score_gpt":0.2342862721496057,"score_spread":0.2208648207653975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}