{"id":"W2074511697","doi":"10.1016/j.scr.2010.08.002","title":"Human embryonic fibroblasts support single cell enzymatic expansion of human embryonic stem cells in xeno-free cultures","year":2010,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Stem Cell Network","keywords":"Foreskin; Embryonic stem cell; Biology; Cell biology; Cell culture; KOSR; Induced pluripotent stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002845877,0.0004674622,0.0005865077,0.0006463121,0.0004011463,0.0001757349,0.002188595,0.0006863454,0.0002274096],"category_scores_gemma":[0.00003196351,0.0004428932,0.0002687672,0.0007158867,0.0005604894,0.00003693299,0.001703038,0.001506761,0.000194625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001331675,"about_ca_system_score_gemma":0.0005634425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001796389,"about_ca_topic_score_gemma":0.0009117275,"domain_scores_codex":[0.9936554,0.0008502801,0.0008385373,0.001237464,0.001752297,0.001666064],"domain_scores_gemma":[0.9962494,0.0001321273,0.0002524591,0.002363838,0.0005889694,0.0004132455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008545198,0.0006018398,0.0004041316,0.001033859,0.00002319929,0.00005312601,0.0003199418,0.0000473004,0.984636,0.00006597096,0.012382,0.0003471579],"study_design_scores_gemma":[0.001804822,0.00187828,0.0004400822,0.0001134344,0.00001071239,0.000009769282,0.0009085064,0.00004298592,0.9894077,0.00008575901,0.004874373,0.0004236177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787443,0.0006049628,0.00001591602,0.00008487239,0.0001804363,0.001179186,0.0000601023,0.00002845364,0.01910175],"genre_scores_gemma":[0.9282484,0.0001047535,0.0001221744,0.00001539119,0.0001755288,0.00009184548,0.0001024475,0.0001124109,0.07102706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05192531,"threshold_uncertainty_score":0.9998023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110260374772597,"score_gpt":0.3200178547399043,"score_spread":0.2889152509921783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}