{"id":"W2074515925","doi":"10.1371/journal.pone.0092325","title":"Human Astrocytes: Secretome Profiles of Cytokines and Chemokines","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":413,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Chemokine; CCL5; Astrocyte; Neuroinflammation; Proinflammatory cytokine; CCL3; Biology; CCL7; CXCL10; Cytokine; Cell biology; CCL2; CXCL1; Immunology; Inflammation; Neuroscience; Central nervous system; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009497755,0.000230632,0.0003029324,0.0005014034,0.0002125241,0.0003099248,0.00005856344,0.0001622955,0.00128292],"category_scores_gemma":[0.0001820301,0.00009789885,0.0002072486,0.0007377389,0.00007539438,0.0001569159,0.0001514722,0.0001912323,0.0006168893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007046522,"about_ca_system_score_gemma":0.0001947578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006679596,"about_ca_topic_score_gemma":0.0007906432,"domain_scores_codex":[0.999855,0.000009824492,0.00001483071,0.00003536026,0.00005484011,0.00003017796],"domain_scores_gemma":[0.9999104,0.00001336112,0.00001743122,0.000007754637,0.0000369874,0.00001412924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004233368,0.00003233774,0.004370723,0.00008919756,0.00001346379,0.0001744849,0.00007330757,0.00004867728,0.9897341,0.00002611418,0.0001523914,0.004861896],"study_design_scores_gemma":[0.00005899169,0.0009066716,0.2055182,0.00005244963,0.00018604,0.004146954,0.0005206696,0.002090685,0.7714034,0.0002821151,0.01479476,0.00003910087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817796,0.004284469,0.00319891,0.0001150125,0.00004571109,0.0001085129,0.008758524,0.00006860805,0.001640498],"genre_scores_gemma":[0.9669438,0.005098867,0.006528523,0.0002005134,0.0001161238,0.0002546551,0.01694405,0.00002538047,0.003888004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00128292,"threshold_uncertainty_score":0.004291832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05993859286726509,"score_gpt":0.2441634177552043,"score_spread":0.1842248248879392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}