{"id":"W2074515925","doi":"10.1371/journal.pone.0092325","title":"Human Astrocytes: Secretome Profiles of Cytokines and Chemokines","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":413,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Chemokine; CCL5; Astrocyte; Neuroinflammation; Proinflammatory cytokine; CCL3; Biology; CCL7; CXCL10; Cytokine; Cell biology; CCL2; CXCL1; Immunology; Inflammation; Neuroscience; Central nervous system; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008554348,0.0001033104,0.0001732461,0.00008694359,0.0001012472,0.00003202019,0.0001151423,0.00003073864,0.0000967166],"category_scores_gemma":[0.0003491049,0.00009614704,0.00002229531,0.0001214815,0.00006829537,0.0001231686,0.00005040121,0.00006831029,0.00001890971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003257901,"about_ca_system_score_gemma":0.000006886244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.680914e-7,"about_ca_topic_score_gemma":0.00000104565,"domain_scores_codex":[0.9990424,0.00008063456,0.0002109968,0.0002586569,0.0002845238,0.0001228238],"domain_scores_gemma":[0.9995136,0.00007183398,0.0001193655,0.0001923219,0.00004394169,0.00005897352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000627542,0.0001283004,0.0001964691,0.00007302133,0.000002379031,7.375346e-7,0.00004298158,0.000002345758,0.9875939,0.01183485,0.000025499,0.00009326365],"study_design_scores_gemma":[0.0002848458,0.0001490551,0.0006397343,0.00003183935,0.00001290102,0.000003002919,0.000004988393,0.001178327,0.9971511,0.0003714538,0.00008520528,0.00008749894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979809,0.000003541324,0.0001232674,0.0002300601,0.00002726915,0.0001793419,0.000007888566,0.0001025686,0.001345177],"genre_scores_gemma":[0.997736,0.00001257443,0.0007289292,0.0003351917,0.00009893598,0.00001733371,0.000002456625,0.00001670419,0.00105183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0114634,"threshold_uncertainty_score":0.3920763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05993859286726509,"score_gpt":0.2441634177552043,"score_spread":0.1842248248879392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}