{"id":"W2074529958","doi":"10.1016/j.tox.2008.03.011","title":"Cytochrome P450 2C11 5′-flanking region and promoter: Regulation by aromatic hydrocarbons in vitro","year":2008,"lang":"en","type":"article","venue":"Toxicology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Aryl hydrocarbon receptor; Luciferase; Transfection; Biology; In vivo; Transcription factor; Cytochrome P450; In vitro; Molecular biology; Mutagenesis; Transcription (linguistics); Chemistry; Biochemistry; Gene; Mutation; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000601191,0.0005437896,0.0006773691,0.0004085934,0.0004340461,0.0006268952,0.0004554118,0.0003777294,0.003244166],"category_scores_gemma":[0.0007628044,0.0006049362,0.0006270141,0.0004509767,0.0006008247,0.0003929825,0.0005191764,0.001148302,0.00113276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007691057,"about_ca_system_score_gemma":0.0009107179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006946123,"about_ca_topic_score_gemma":0.009020837,"domain_scores_codex":[0.9990811,0.0002448359,0.00006415263,0.0002619241,0.0001497954,0.0001980381],"domain_scores_gemma":[0.9991965,0.0004885158,0.00006358441,0.00006977483,0.00009228795,0.00008930042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00046548,0.0001292507,0.0004784931,0.00005955703,0.0000103649,0.00004479428,0.00008451984,0.0001377099,0.9967766,0.0001870591,0.0001879215,0.001438203],"study_design_scores_gemma":[0.00003529671,0.000167444,0.005241374,0.00001827976,0.00003117827,0.0001802985,0.0001016402,0.001333967,0.9896944,0.00008179836,0.003098055,0.0000163311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704975,0.002426513,0.01944217,0.0005582792,0.0001408082,0.0001219207,0.003021574,0.0002431459,0.003548106],"genre_scores_gemma":[0.9595501,0.001130812,0.01420133,0.000228216,0.00006899959,0.0001496828,0.01282451,0.0002010585,0.01164529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006946123,"threshold_uncertainty_score":0.01381135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.012430637828269,"score_gpt":0.2194916694221002,"score_spread":0.2070610315938312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}