{"id":"W2074550903","doi":"10.1007/s00125-013-2998-6","title":"Modulation of p75NTR prevents diabetes- and proNGF-induced retinal inflammation and blood–retina barrier breakdown in mice and rats","year":2013,"lang":"en","type":"article","venue":"Diabetologia","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Eye Institute","keywords":"Neurotrophin; Retina; Nerve growth factor; Retinal; Muller glia; Blood–retinal barrier; Endocrinology; Biology; Internal medicine; Neurodegeneration; Low-affinity nerve growth factor receptor; Diabetes mellitus; Cell biology; Receptor; Diabetic retinopathy; Neuroscience; Medicine; Stem cell; Progenitor cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003652798,0.001019224,0.0006178442,0.001149423,0.0003968797,0.000523158,0.0007316059,0.0007643889,0.002225228],"category_scores_gemma":[0.0003180429,0.0003953305,0.0006397692,0.0003196107,0.0008301329,0.0008050282,0.0002977844,0.002150397,0.0005895824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005911745,"about_ca_system_score_gemma":0.0007280899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002780026,"about_ca_topic_score_gemma":0.003706783,"domain_scores_codex":[0.9994839,0.00005768741,0.00005339982,0.0001083837,0.00008629073,0.0002103622],"domain_scores_gemma":[0.9993474,0.00005100127,0.0002158219,0.00008208388,0.00004233108,0.000261303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003736815,0.000577738,0.0002599962,0.00007915294,0.00002509191,0.0001867124,0.00005639557,0.0001419361,0.9907414,0.0003327217,0.0001801122,0.003681988],"study_design_scores_gemma":[0.0003024472,0.003251276,0.003768537,0.00002114056,0.0000953232,0.0002556164,0.0001582186,0.001095794,0.9884172,0.0001698158,0.002440602,0.00002402912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933995,0.001725284,0.002072545,0.0003727638,0.0001873176,0.00005511506,0.0004961931,0.0002352748,0.00145597],"genre_scores_gemma":[0.9846635,0.002019648,0.003284639,0.000247427,0.00007543428,0.0001490069,0.0005931697,0.00007257247,0.008894525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002780026,"threshold_uncertainty_score":0.007444084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008124864515844146,"score_gpt":0.236981388700952,"score_spread":0.2288565241851079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}