{"id":"W2074570966","doi":"10.1126/science.1136611","title":"Structural Insight into the Transglycosylation Step of Bacterial Cell-Wall Biosynthesis","year":2007,"lang":"en","type":"article","venue":"Science","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":301,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Peptidoglycan; Cell wall; Bacterial cell structure; Glycosyltransferase; Enzyme; Bacteria; Biochemistry; Biosynthesis; Phosphofructokinase 2; Chemistry; Lipid II; Bifunctional; Stereochemistry; Biology; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002916,0.0004669273,0.0002182433,0.0001280396,0.0001547399,0.0003224251,0.0003394241,0.0003769381,0.000899725],"category_scores_gemma":[0.0001366607,0.0001988808,0.0001352561,0.0001663554,0.0002053195,0.0004543671,0.0001340677,0.0008088463,0.0003719348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004490823,"about_ca_system_score_gemma":0.0004788219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009118154,"about_ca_topic_score_gemma":0.00116465,"domain_scores_codex":[0.9999597,0.000005741744,0.000002379269,0.000007404572,0.000016035,0.000008707162],"domain_scores_gemma":[0.9999619,0.000007239982,0.00001056941,0.000003613291,0.000005016089,0.00001164517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002107112,0.00009799159,0.0007183061,0.0001398978,0.000008296512,0.0004341934,0.00006170412,0.007923559,0.9766406,0.004590687,0.0002733555,0.008900723],"study_design_scores_gemma":[0.0002013943,0.0016435,0.01895248,0.0001099802,0.0000957171,0.003360427,0.0004087968,0.07932847,0.836518,0.01114631,0.04815178,0.00008306027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838447,0.00496866,0.005890153,0.0007449412,0.00004963791,0.00001394744,0.0002059596,0.0001111501,0.004170794],"genre_scores_gemma":[0.983171,0.005226812,0.00897296,0.0001583004,0.00002071068,0.000008959503,0.0005327833,0.00001176538,0.001896611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009118154,"threshold_uncertainty_score":0.003258288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006624029281540542,"score_gpt":0.2236776964175604,"score_spread":0.2170536671360199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}