{"id":"W2074589748","doi":"10.1177/089719002237667","title":"Renal Drug Transport and Drug-Drug Interactions","year":2002,"lang":"en","type":"article","venue":"Journal of Pharmacy Practice","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Merck Canada; Canadian Foundation for AIDS Research; amfAR, The Foundation for AIDS Research","keywords":"Reabsorption; Drug; Renal physiology; Pharmacology; Transporter; Organic anion transporter 1; Medicine; Organic cation transport proteins; Efflux; Secretion; Kidney; Chemistry; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006981448,0.0001651014,0.0003862058,0.0001367909,0.0001593321,0.00002498421,0.00008913212,0.0000125135,0.001096034],"category_scores_gemma":[0.0005429884,0.0001169642,0.0001617355,0.0001730542,0.00008847001,0.0009977868,0.00002895604,0.0009899804,0.0000360542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006421864,"about_ca_system_score_gemma":0.0000349862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003972487,"about_ca_topic_score_gemma":0.000006098632,"domain_scores_codex":[0.998561,0.0001915872,0.0005019525,0.0001501661,0.0003801844,0.000215156],"domain_scores_gemma":[0.9977726,0.001100499,0.000483469,0.00007939861,0.0002534543,0.000310546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008930534,0.007744225,0.01665024,0.0005388665,0.003718911,0.01171751,0.01267627,0.0001007097,0.1565051,0.0002066095,0.7178602,0.06335086],"study_design_scores_gemma":[0.00691348,0.0001558408,0.002779101,0.0001202402,0.001867133,0.005100325,0.0005956449,0.0008617713,0.01029956,0.00003305272,0.9711055,0.0001683932],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8465885,0.006290243,0.000106348,0.1229872,0.0008753041,0.0002963417,0.000007276053,0.00003714214,0.02281165],"genre_scores_gemma":[0.9832639,0.00530182,0.001085363,0.005757496,0.0008226008,0.000004078923,6.379218e-7,0.00001477573,0.003749395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2532453,"threshold_uncertainty_score":0.9998171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04993300676132833,"score_gpt":0.3824866625033072,"score_spread":0.3325536557419789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}