{"id":"W2074622472","doi":"10.1002/pbc.24191","title":"Expression and stability of hypoxia inducible factor 1α in osteosarcoma","year":2012,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"U.S. Department of Defense","keywords":"Osteosarcoma; Hypoxia (environmental); Transcription factor; Cancer research; Cell culture; Immunohistochemistry; Medicine; Hypoxia-inducible factors; Cell; Pathology; Biology; Chemistry; Gene; Oxygen; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001881934,0.0001631323,0.0001984141,0.0004377181,0.0002189626,0.0002443446,0.0001078343,0.0001775182,0.001073479],"category_scores_gemma":[0.0002706634,0.0001423294,0.000157838,0.0003433584,0.0001617979,0.0001281622,0.0001429374,0.0002520101,0.0004216661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003674629,"about_ca_system_score_gemma":0.0002351089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006973765,"about_ca_topic_score_gemma":0.0006839855,"domain_scores_codex":[0.9998699,0.00001055581,0.00001292565,0.00003217359,0.00005289409,0.00002146582],"domain_scores_gemma":[0.9997692,0.0000264458,0.00008784796,0.0000156969,0.00006787295,0.0000331084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001314848,0.00001767408,0.002509893,0.00008213519,0.00000753478,0.0001143637,0.00005485882,0.00006271411,0.9933121,0.00006567758,0.00006976003,0.003571771],"study_design_scores_gemma":[0.0000359624,0.0007756638,0.1240196,0.00003529579,0.000104836,0.003306519,0.0002321076,0.001632242,0.8559242,0.0002618059,0.013655,0.00001682129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864123,0.00719818,0.004176758,0.00009108989,0.00003212603,0.00003133058,0.0007823687,0.00006318145,0.001212723],"genre_scores_gemma":[0.98992,0.003470892,0.002755255,0.0000380033,0.00002361367,0.00003672732,0.001736445,0.00001996079,0.001999092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073479,"threshold_uncertainty_score":0.00359112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731382126532033,"score_gpt":0.2596016478919469,"score_spread":0.2422878266266266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}