{"id":"W2074622472","doi":"10.1002/pbc.24191","title":"Expression and stability of hypoxia inducible factor 1α in osteosarcoma","year":2012,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"U.S. Department of Defense","keywords":"Osteosarcoma; Hypoxia (environmental); Transcription factor; Cancer research; Cell culture; Immunohistochemistry; Medicine; Hypoxia-inducible factors; Cell; Pathology; Biology; Chemistry; Gene; Oxygen; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765002,0.0001455323,0.000217021,0.00006570572,0.00002852484,0.000006667903,0.0001058483,0.0001576103,0.00008787384],"category_scores_gemma":[0.00006066065,0.0001334903,0.00005593894,0.0001554949,0.00004609358,0.00001314755,0.0001201717,0.0001089487,0.000001095099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009458818,"about_ca_system_score_gemma":0.0001201291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002913972,"about_ca_topic_score_gemma":0.0001139682,"domain_scores_codex":[0.9989567,0.00005646301,0.0002418837,0.000285814,0.0001377206,0.0003213785],"domain_scores_gemma":[0.9994014,0.00001769964,0.0001113604,0.0002857978,0.00005087002,0.0001328967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004718391,0.0001433002,0.3759576,0.00008760548,0.00001105605,1.058988e-7,0.0002183436,6.949468e-7,0.6208354,0.000003966335,0.0003548923,0.00233989],"study_design_scores_gemma":[0.001265435,0.00007589397,0.2932544,0.000009831821,0.00008134464,0.000003026656,0.00006647134,7.844174e-7,0.6902,0.00001244129,0.01482879,0.0002015898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9283062,0.07052863,0.00001191429,0.00002157681,0.0006933452,0.0001759404,0.00008551138,0.000006261074,0.000170641],"genre_scores_gemma":[0.9887169,0.008427494,0.0002090739,0.00004800232,0.002469979,0.00005271323,0.00001271613,0.00001734301,0.00004575398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0827032,"threshold_uncertainty_score":0.5443577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731382126532033,"score_gpt":0.2596016478919469,"score_spread":0.2422878266266266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}