{"id":"W2074710780","doi":"10.1016/j.envpol.2012.10.015","title":"An endocrine disruptor, bisphenol A, affects development in the protochordate Ciona intestinalis: Hatching rates and swimming behavior alter in a dose-dependent manner","year":2012,"lang":"en","type":"article","venue":"Environmental Pollution","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Ciona intestinalis; Endocrine disruptor; Biology; Bisphenol A; Hatching; Ciona; Gamete; Endocrine system; Larva; Internal medicine; Endocrinology; Embryo; Toxicology; Andrology; Zoology; Human fertilization; Cell biology; Chemistry; Anatomy; Ecology; Biochemistry; Hormone; Medicine; Epoxy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001299185,0.0006094144,0.0002606843,0.000544233,0.0003415415,0.0004252063,0.0004403275,0.0005523792,0.001186272],"category_scores_gemma":[0.0003618569,0.0004263255,0.0002489682,0.0002063817,0.0004523514,0.0003274919,0.0003603986,0.0006221015,0.0001941604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006708637,"about_ca_system_score_gemma":0.0004333102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008415659,"about_ca_topic_score_gemma":0.01450041,"domain_scores_codex":[0.9997981,0.00002409471,0.00001569924,0.00005391279,0.00006263877,0.00004552463],"domain_scores_gemma":[0.9994766,0.0001038866,0.0001344971,0.00005398027,0.00009243839,0.0001386178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002409087,0.00003068096,0.001417319,0.00002268342,0.0000102215,0.00005285182,0.00003510544,0.00003505071,0.9972879,0.0000183117,0.00002467264,0.0008244063],"study_design_scores_gemma":[0.00003384717,0.001110861,0.1390804,0.0000102942,0.0000786155,0.0002691304,0.0002432399,0.0006492859,0.8568136,0.00006357649,0.001616316,0.00003075906],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985329,0.0003196804,0.0002637473,0.00005103606,0.00002195348,0.000009075765,0.0001565467,0.00002307336,0.0006221223],"genre_scores_gemma":[0.9935887,0.0007191342,0.0007755196,0.00008807635,0.000008521007,0.00002784363,0.0003946437,0.00002327787,0.004374292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008415659,"threshold_uncertainty_score":0.01673335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01069471366814749,"score_gpt":0.3156096875748034,"score_spread":0.3049149739066559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}