{"id":"W2074725166","doi":"10.1016/s0378-1119(01)00445-0","title":"Transcriptional activity of the SHP-1 gene in MCF7 cells is differentially regulated by binding of NF-Y factor to two distinct CCAAT-elements","year":2001,"lang":"en","type":"article","venue":"Gene","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; University of New England","keywords":"CAAT box; Biology; Molecular biology; Trichostatin A; Promoter; Transcription factor; Ccaat-enhancer-binding proteins; Repressor; TATA box; Response element; Histone deacetylase; Gene; Gene expression; DNA-binding protein; Histone; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007963089,0.0001466355,0.000173847,0.00003604113,0.00003595442,0.000006926658,0.0002704262,0.00007372408,0.00009558048],"category_scores_gemma":[0.000019808,0.0001226072,0.00009262429,0.0001470563,0.00005263296,0.000004280496,0.0001186439,0.00005519198,0.000002358538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002330476,"about_ca_system_score_gemma":0.00004329756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519071,"about_ca_topic_score_gemma":0.00009525818,"domain_scores_codex":[0.9989849,0.00005752107,0.0002652919,0.0002788616,0.0001987256,0.0002147061],"domain_scores_gemma":[0.9994207,0.000006390859,0.0001306254,0.0003419027,0.00004486826,0.00005549592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000175801,0.0001572898,0.006018556,0.00001359598,0.00004257048,7.042731e-7,0.00002658819,0.00001919988,0.9908218,0.000004598804,0.0004641289,0.002255157],"study_design_scores_gemma":[0.000781304,0.00009508086,0.04677167,0.00001647411,0.00001444459,0.000001382235,0.00000253342,0.0000186737,0.9508302,0.00001404866,0.001336241,0.0001179833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961203,0.0005895975,0.001230264,0.0001073149,0.0001137555,0.0003207741,0.001498318,0.000003812861,0.00001582518],"genre_scores_gemma":[0.9988908,0.00005565637,0.0004535273,0.00005228107,0.00003885015,0.00001634477,0.0002157653,0.00001628231,0.0002605183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04075311,"threshold_uncertainty_score":0.4999777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261780109203795,"score_gpt":0.2488764272490747,"score_spread":0.2362586261570367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}