{"id":"W2074754565","doi":"10.4161/cc.10.8.15358","title":"Primary microcephaly 3 (MCPH3): Revisiting two critical mutations","year":2011,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Microcephaly; Biology; Genetics; Mutation; Primary (astronomy); Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009831628,0.0003145343,0.0002742462,0.00005971662,0.000130029,0.0000514243,0.0003541007,0.0006815637,0.0001533508],"category_scores_gemma":[0.00004441409,0.0003430786,0.0002319274,0.00005623467,0.0001349784,0.000004073062,0.0001894108,0.0006819612,0.0002053149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002842015,"about_ca_system_score_gemma":0.0001278069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003164548,"about_ca_topic_score_gemma":0.000003952156,"domain_scores_codex":[0.9984156,0.00007844307,0.000315105,0.0006056519,0.0001219119,0.0004632523],"domain_scores_gemma":[0.9990931,0.00003504761,0.0001142756,0.0005638546,0.0001199366,0.00007379655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000765274,0.00003525639,0.00003660998,0.00033693,0.00003756076,0.00008199176,0.00003537864,0.000002603805,0.3493814,0.000009896921,0.6488895,0.001145139],"study_design_scores_gemma":[0.000290603,0.00005588478,0.00003134448,0.00005867771,0.000117676,0.00005472475,0.00001307757,0.000009336781,0.1080454,0.0001491758,0.8906974,0.0004767251],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.2075899,0.0330021,0.01952394,0.1907721,0.004470514,0.002670021,0.001775355,0.0004104603,0.5397856],"genre_scores_gemma":[0.05808832,0.0009064694,0.01014946,0.8742859,0.01751794,0.0001181857,0.01256034,0.0003943272,0.02597903],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6835138,"threshold_uncertainty_score":0.9999021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008679601404190811,"score_gpt":0.2416033193860234,"score_spread":0.2329237179818326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}