{"id":"W2074783908","doi":"10.1016/j.ymeth.2013.07.032","title":"X-ray crystallography and NMR as tools for the study of protein tyrosine phosphatases","year":2013,"lang":"en","type":"review","venue":"Methods","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Protein tyrosine phosphatase; Computational biology; Phosphatase; Function (biology); Mode of action; Protein structure; Identification (biology); Tyrosine; Computer science; Chemistry; Biochemistry; Biology; Phosphorylation; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002145616,0.001960373,0.0020861,0.002533294,0.0003473765,0.001270757,0.002544473,0.001704165,0.002607934],"category_scores_gemma":[0.001419048,0.0008400181,0.0007173038,0.003607636,0.00205765,0.002462113,0.001540088,0.003993602,0.003000185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001482523,"about_ca_system_score_gemma":0.001460727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001410594,"about_ca_topic_score_gemma":0.001607491,"domain_scores_codex":[0.9994889,0.00008268852,0.00004236899,0.00007664428,0.0002554585,0.00005381994],"domain_scores_gemma":[0.9993765,0.0002713182,0.00008530186,0.00004389586,0.000158036,0.00006492685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001097117,0.0001255895,0.0001617854,0.01277219,0.0001143814,0.0001674366,0.00006648461,0.001288721,0.01135668,0.01976691,0.03919756,0.9148726],"study_design_scores_gemma":[0.00003660686,0.00006180588,0.0003178412,0.001028088,0.0000707002,0.0005823923,0.00002982726,0.0003913038,0.004321232,0.006249472,0.986873,0.00003768168],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001767122,0.9959409,0.002176547,0.0003194231,0.0002976647,0.000009909793,0.00003496894,0.00003345088,0.001010562],"genre_scores_gemma":[0.0007590195,0.9957781,0.001908629,0.0002007299,0.0002250982,0.00001889232,0.00008156343,0.000007385029,0.00102061],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002607934,"threshold_uncertainty_score":0.01134723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07669495651052179,"score_gpt":0.4112162762724499,"score_spread":0.3345213197619282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}