{"id":"W2074783908","doi":"10.1016/j.ymeth.2013.07.032","title":"X-ray crystallography and NMR as tools for the study of protein tyrosine phosphatases","year":2013,"lang":"en","type":"review","venue":"Methods","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Protein tyrosine phosphatase; Computational biology; Phosphatase; Function (biology); Mode of action; Protein structure; Identification (biology); Tyrosine; Computer science; Chemistry; Biochemistry; Biology; Phosphorylation; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001254293,0.0005006338,0.001178948,0.00008164215,0.0001323397,0.0001042579,0.0006182269,0.0002863728,0.00002733952],"category_scores_gemma":[0.001534308,0.0003122992,0.0003851772,0.0002387706,0.0002020186,0.000009732577,0.0004210333,0.0001713668,0.000001734705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008360478,"about_ca_system_score_gemma":0.0001293274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001111724,"about_ca_topic_score_gemma":0.000005972637,"domain_scores_codex":[0.9975142,0.0007038058,0.0006514332,0.0006605223,0.0001601878,0.0003098759],"domain_scores_gemma":[0.9975982,0.0005708026,0.0005404782,0.001063592,0.0001445362,0.00008243931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003611995,0.0001833305,0.000001658532,0.003222669,0.0004810761,9.877294e-7,0.00001307435,8.92646e-7,0.001123581,0.0002402866,0.0007750813,0.9939212],"study_design_scores_gemma":[0.0004675732,0.001392639,0.000005628936,0.000782802,0.000846049,0.000008422377,0.00006843591,0.000001431178,0.01803644,0.0001063856,0.9779373,0.000346899],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007728345,0.9804947,0.009462373,0.00001347647,0.00009518683,0.009330273,0.0004942369,0.00001365791,0.0000187981],"genre_scores_gemma":[0.00004731262,0.9176872,0.07570676,0.0000367786,0.0001603329,0.005588756,0.00046255,0.00007940207,0.0002308673],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9935743,"threshold_uncertainty_score":0.9999329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07669495651052179,"score_gpt":0.4112162762724499,"score_spread":0.3345213197619282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}