{"id":"W2074794025","doi":"10.1099/vir.0.018069-0","title":"Nuclear assortment of eIF4E coincides with shut-off of host protein synthesis upon poliovirus infection","year":2010,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"EIF4G; EIF4E; Biology; Poliovirus; Initiation factor; Virology; Cell biology; Cleavage (geology); Eukaryotic translation; Protein biosynthesis; Internal ribosome entry site; Translation (biology); Virus; Messenger RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005093107,0.0001188144,0.0005156708,0.0004483243,0.0000609083,0.000005524858,0.00009049391,0.000210446,0.000375845],"category_scores_gemma":[0.0001899548,0.00008104961,0.0001521993,0.0001973681,0.0002865225,0.0001063408,0.00004100265,0.0006419233,0.000006848633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004728745,"about_ca_system_score_gemma":0.000169343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003730949,"about_ca_topic_score_gemma":0.0001692929,"domain_scores_codex":[0.998795,0.0001416942,0.0005091583,0.0001103079,0.0002287784,0.0002150072],"domain_scores_gemma":[0.9987391,0.00005254549,0.0005152258,0.0002083024,0.000397992,0.00008687295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001724553,0.0004601784,0.03473001,0.00003409153,0.0003539805,0.0000400931,0.00004941316,0.00001476483,0.9570606,0.0004598329,0.0001491935,0.004923275],"study_design_scores_gemma":[0.001896877,0.01163458,0.4454401,0.0000847544,0.0002318352,0.001694217,0.00003185929,0.00009427645,0.5314211,0.00007650732,0.007289878,0.0001040241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978579,0.0001810813,0.00003746467,0.0008737766,0.0001769862,0.0002103109,0.000004426771,0.000006986636,0.0006510117],"genre_scores_gemma":[0.9982953,0.0002628162,0.0009958461,0.00007706918,0.0001908731,0.000007362797,9.362687e-7,0.00001918901,0.0001505787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4256395,"threshold_uncertainty_score":0.4115239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354842352418668,"score_gpt":0.2854414501246946,"score_spread":0.271893026600508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}