{"id":"W2074805250","doi":"10.1007/s11060-013-1238-8","title":"Optimization of the route of platinum drugs administration to optimize the concomitant treatment with radiotherapy for glioblastoma implanted in the Fischer rat brain","year":2013,"lang":"en","type":"article","venue":"Journal of Neuro-Oncology","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Carboplatin; Cisplatin; Medicine; Oxaliplatin; Radiation therapy; Toxicity; Pharmacology; Concomitant; Glioma; Chemotherapy; Drug; Liposome; Brain tumor; Cancer; Internal medicine; Cancer research; Chemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007942015,0.0001354587,0.0003622421,0.00007375373,0.00006873557,0.00003663689,0.0003960559,0.00006326746,0.00005733413],"category_scores_gemma":[0.0001667921,0.00005877742,0.00009720187,0.000234881,0.0001361297,0.0001738472,0.000021367,0.0001098836,0.000001375372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001744754,"about_ca_system_score_gemma":0.000460582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002930978,"about_ca_topic_score_gemma":0.00008548693,"domain_scores_codex":[0.9980522,0.0006772121,0.0006804962,0.0001311019,0.0002642036,0.0001947359],"domain_scores_gemma":[0.9966496,0.001942126,0.000874107,0.0002547036,0.0002306296,0.00004878317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00366524,0.0003286882,0.0002777692,0.000007483618,0.00002815497,0.00001678697,0.002813447,0.07877479,0.9116954,0.00003788275,0.001492933,0.0008614541],"study_design_scores_gemma":[0.007893361,0.02402142,0.0009865102,0.00006805442,0.0001126621,0.0007325248,0.00212531,0.02514437,0.9359926,0.00004665364,0.002728845,0.000147677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756519,0.00003793073,0.002712026,0.02016177,0.0002839918,0.001097566,0.00002033886,0.000004154581,0.00003038817],"genre_scores_gemma":[0.9912155,0.00001792475,0.007169564,0.001428618,0.00007231031,0.0000620779,7.611513e-7,0.00001431762,0.00001889868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05363041,"threshold_uncertainty_score":0.2396874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379339001760389,"score_gpt":0.2721746432400365,"score_spread":0.2583812532224327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}