{"id":"W2074813958","doi":"10.1038/cdd.2014.19","title":"IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Deutsches Zentrum für Infektionsforschung; Alexander von Humboldt-Stiftung; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"IRF4; CD8; Lymphocytic choriomeningitis; Biology; Immunology; Cytotoxic T cell; T cell; Interferon regulatory factors; Immunopathology; Transcription factor; Immune system; Cancer research; Innate immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002468741,0.0004658067,0.0002561148,0.0002983334,0.0002734601,0.000415725,0.000323917,0.0005186736,0.001854895],"category_scores_gemma":[0.0003722384,0.0002466563,0.0002671161,0.000105774,0.0004033415,0.0003946719,0.0004243365,0.0007468808,0.0008263682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005069521,"about_ca_system_score_gemma":0.0003373435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005044129,"about_ca_topic_score_gemma":0.0005617774,"domain_scores_codex":[0.9997192,0.00005498515,0.00002324978,0.00004589294,0.00006008594,0.00009657882],"domain_scores_gemma":[0.9997144,0.00003671379,0.000112567,0.00003644754,0.00003494986,0.00006489606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001887146,0.00001464615,0.0005921319,0.00002133476,0.000003193855,0.00005763901,0.00001157925,0.0000536008,0.9974776,0.00009090939,0.00003364431,0.001454985],"study_design_scores_gemma":[0.00003830014,0.0003178779,0.02601153,0.00001552968,0.00002624162,0.0009760019,0.00008940739,0.001448738,0.9675843,0.0005012193,0.002979222,0.00001162737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926733,0.002480209,0.002893245,0.0001466904,0.00002794862,0.00001970189,0.0002867731,0.0001605774,0.001311549],"genre_scores_gemma":[0.9938189,0.0005654522,0.002836533,0.00003852184,0.00001579503,0.00004286387,0.0005920765,0.00003033804,0.002059542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001854895,"threshold_uncertainty_score":0.006205261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00887474231257234,"score_gpt":0.2148795052492469,"score_spread":0.2060047629366745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}