{"id":"W2074813958","doi":"10.1038/cdd.2014.19","title":"IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Deutsches Zentrum für Infektionsforschung; Alexander von Humboldt-Stiftung; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"IRF4; CD8; Lymphocytic choriomeningitis; Biology; Immunology; Cytotoxic T cell; T cell; Interferon regulatory factors; Immunopathology; Transcription factor; Immune system; Cancer research; Innate immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279995,0.0001548592,0.0001710547,0.00009930825,0.0003438338,0.00005904871,0.00002167583,0.0001768802,0.00009208704],"category_scores_gemma":[0.00006079142,0.0001296778,0.00005968327,0.00004384027,0.00003325731,0.0002217107,0.00001654387,0.0001399135,0.00003420523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002111317,"about_ca_system_score_gemma":0.000007382674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003251449,"about_ca_topic_score_gemma":0.00001462557,"domain_scores_codex":[0.9992345,0.00009403684,0.0001697753,0.0002755705,0.00003052939,0.0001955985],"domain_scores_gemma":[0.9995447,0.0001580562,0.00009222941,0.0001043071,0.00007032126,0.00003032247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001493828,0.0004664126,0.1598616,0.000437719,0.0001316479,5.165503e-7,0.0003118806,0.00001380972,0.8208343,0.003188244,0.003183354,0.01007669],"study_design_scores_gemma":[0.01228973,0.003790626,0.6695587,0.0001992866,0.001148518,0.00004774979,0.0005587176,0.003705835,0.2240123,0.001868852,0.08181661,0.001003],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8827303,0.000524749,0.1128339,0.00007029166,0.002134986,0.0002205736,0.000001912137,0.00007016183,0.001413145],"genre_scores_gemma":[0.9964871,0.00006216657,0.00007258559,0.0001489615,0.00006459865,0.00004048521,0.0002149852,0.00001616222,0.00289293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.596822,"threshold_uncertainty_score":0.5288108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00887474231257234,"score_gpt":0.2148795052492469,"score_spread":0.2060047629366745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}