{"id":"W2074825624","doi":"10.3390/md9102046","title":"The Chemical Synthesis of Tetrodoxin: An Ongoing Quest","year":2011,"lang":"en","type":"review","venue":"Marine Drugs","topic":"Oxidative Organic Chemistry Reactions","field":"Chemistry","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Computational biology; Biochemical engineering; Stereochemistry; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002529932,0.0005021304,0.001210768,0.0000394857,0.0001195332,0.00004372519,0.001036664,0.0003923269,0.002649679],"category_scores_gemma":[0.0006721936,0.0003626163,0.0004815063,0.0002160585,0.0002350361,0.00004965346,0.0005852579,0.0007339874,0.0001023966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002589713,"about_ca_system_score_gemma":0.0002533279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001532609,"about_ca_topic_score_gemma":0.00001341169,"domain_scores_codex":[0.9980606,0.00005006702,0.0007532467,0.0005361035,0.0002378813,0.000362099],"domain_scores_gemma":[0.9966996,0.0009650027,0.0006421263,0.001463991,0.00008072581,0.0001485337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000483898,0.0001297542,0.0000108143,0.007826742,0.0002365646,0.000003022421,0.00003740958,4.907136e-9,0.001621484,0.0001709718,0.000275391,0.989683],"study_design_scores_gemma":[0.00005955607,0.000003647094,7.01133e-7,0.002114984,0.0006544059,0.000049319,0.00007321257,0.000001194653,0.04070818,0.00003895186,0.9559437,0.0003521353],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000279078,0.7008169,6.714117e-7,0.00002206746,0.0001097142,0.0001463851,0.0001281078,0.0001581811,0.2983389],"genre_scores_gemma":[0.0005753006,0.9927055,0.0001478064,0.000002854035,0.0004998441,0.0001232237,0.000185596,0.0001387602,0.005621159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9893309,"threshold_uncertainty_score":0.9998826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0267886540180205,"score_gpt":0.2865216384079138,"score_spread":0.2597329843898933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}