{"id":"W2074858838","doi":"10.1016/s0168-1702(03)00161-8","title":"Nucleolar-cytoplasmic shuttling of PRRSV nucleocapsid protein: a simple case of molecular mimicry or the complex regulation by nuclear import, nucleolar localization and nuclear export signal sequences","year":2003,"lang":"en","type":"review","venue":"Virus Research","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of General Medical Sciences; National Institutes of Health; Iowa State University; U.S. Department of Agriculture","keywords":"Biology; Nuclear localization sequence; Nucleolus; NLS; Nuclear export signal; Nuclear transport; Cell biology; Arterivirus; Porcine reproductive and respiratory syndrome virus; Cytoplasm; Fusion protein; Green fluorescent protein; Signal peptide; Nuclear protein; Viral replication; Gene; Molecular biology; Cell nucleus; Virology; Peptide sequence; Genetics; Virus; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390955,0.0008274218,0.001352383,0.0009445926,0.0001670381,0.000672772,0.0009200107,0.0007901272,0.001143973],"category_scores_gemma":[0.0002496537,0.0002258507,0.0002852081,0.001016704,0.0004288545,0.001070705,0.0003114788,0.0007425362,0.001399099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004530935,"about_ca_system_score_gemma":0.0003775744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005405987,"about_ca_topic_score_gemma":0.0008328874,"domain_scores_codex":[0.9999104,0.00001131601,0.00001180191,0.00002395714,0.00003241209,0.00001013865],"domain_scores_gemma":[0.9999106,0.00004162225,0.00001876548,0.000005860843,0.00001603267,0.000007074347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001204032,0.00006910674,0.000136914,0.007829737,0.00006661769,0.0006559551,0.00005594092,0.0005452087,0.02296489,0.005054901,0.009886102,0.9526142],"study_design_scores_gemma":[0.00003028525,0.0001913791,0.0005323201,0.0005230083,0.00008437051,0.002965675,0.00004224309,0.0001815371,0.0103546,0.00147404,0.9836006,0.00001997513],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009399937,0.9953484,0.001232145,0.0001185444,0.0002589862,0.0000128545,0.0000256793,0.00002441328,0.002039071],"genre_scores_gemma":[0.004138072,0.9917392,0.001345574,0.0001769678,0.000129101,0.0000184756,0.0000957058,0.000004608249,0.002352329],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001352383,"threshold_uncertainty_score":0.003826916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1454705266404153,"score_gpt":0.3650501208325166,"score_spread":0.2195795941921014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}