{"id":"W2074868901","doi":"10.1038/cddis.2013.100","title":"BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; Manitoba Health Research Council; CancerCare Manitoba Foundation; U.S. Department of Defense","keywords":"Glioma; Temozolomide; Programmed cell death; Apoptosis; Cancer research; Gene knockdown; Biology; Repressor; Molecular biology; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009843541,0.0002128073,0.0001858625,0.00007837898,0.00007414455,0.00003201852,0.00009561539,0.0001774489,0.0001149306],"category_scores_gemma":[0.0000258126,0.0001875022,0.00008379051,0.0000534575,0.00002914703,0.0000232897,0.00005159984,0.00007279911,0.000005725249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009939991,"about_ca_system_score_gemma":0.00007890265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000643324,"about_ca_topic_score_gemma":0.00000290791,"domain_scores_codex":[0.998748,0.0000715182,0.0002691919,0.0004909015,0.0001688148,0.000251564],"domain_scores_gemma":[0.9991133,0.00001274822,0.00009774807,0.0002674743,0.00005250848,0.000456233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00024561,0.0002591753,0.008042017,0.0001397425,0.00000726343,0.000005948395,0.00009478163,0.00001641633,0.9899961,0.0001801796,0.0001195982,0.0008932004],"study_design_scores_gemma":[0.002742482,0.000344461,0.1397153,0.00009997091,0.00006126516,0.000005379589,0.00007494107,0.0003412324,0.8520088,0.002438785,0.001787444,0.0003798773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951154,0.002758788,0.0001977809,0.00004089844,0.00008407517,0.0004874326,0.00003249732,0.00000957153,0.001273533],"genre_scores_gemma":[0.9966445,0.0009113001,0.0006585115,0.00007767015,0.00007315507,0.00005815789,0.0002019251,0.00002319554,0.001351559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1379872,"threshold_uncertainty_score":0.764612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246536394814146,"score_gpt":0.2329507546942207,"score_spread":0.2204853907460793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}