{"id":"W2074959034","doi":"10.1016/j.ab.2013.11.019","title":"Kras gene codon 12 mutation detection enabled by gold nanoparticles conducted in a nanobioarray chip","year":2013,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oligonucleotide; KRAS; Mutant; Colloidal gold; Polydimethylsiloxane; Molecular biology; Polymerase chain reaction; Materials science; Gene; Nanotechnology; Mutation; Nanoparticle; Chemistry; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552433,0.0002470851,0.0002376203,0.00005855097,0.00005787805,0.00005580668,0.0001556399,0.0003482304,0.00001978195],"category_scores_gemma":[0.0001529277,0.0002256323,0.0001208862,0.0002859634,0.0001907162,0.00001252704,0.00004823236,0.0001579315,0.00001758931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005299617,"about_ca_system_score_gemma":0.00004474732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001246459,"about_ca_topic_score_gemma":0.00005178294,"domain_scores_codex":[0.9984198,0.00005664711,0.0003866694,0.0005757142,0.0001724369,0.0003886953],"domain_scores_gemma":[0.9992139,0.00001972094,0.0001118817,0.0003735462,0.0001332559,0.0001477437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004054244,0.0001099888,0.0004504953,0.00001469195,0.00005602442,0.000004832939,0.000005215555,0.000002845387,0.9954863,0.000003620013,0.001978013,0.001847475],"study_design_scores_gemma":[0.00041075,0.0001046024,0.0002721352,0.00001619237,0.00003900907,0.00002404459,0.00005844602,0.0006819078,0.9971991,0.0001424044,0.0007485527,0.0003028901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983407,0.0002534702,0.0004540123,0.0002686951,0.00002486048,0.0001694517,0.0000184602,0.00006052877,0.0004098297],"genre_scores_gemma":[0.9971079,0.0001352874,0.0007758793,0.0002582557,0.00009516603,0.00003113833,0.0003765984,0.00002293903,0.001196827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00171281,"threshold_uncertainty_score":0.9201021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007268796514514344,"score_gpt":0.2416710566515034,"score_spread":0.234402260136989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}