{"id":"W2074966996","doi":"10.1089/hum.2005.16.1227","title":"Product-Enhanced Reverse Transcriptase Assay for Replication-Competent Retrovirus and Lentivirus Detection","year":2005,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Food and Drug Administration; Vector Institute","keywords":"Reverse transcriptase; Lentivirus; Retrovirus; Virology; Biology; Molecular biology; Virus; Polymerase chain reaction; Gene; Genetics; Viral disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003992788,0.002317485,0.001629502,0.002583072,0.0006851592,0.001206699,0.001658979,0.001331725,0.008135125],"category_scores_gemma":[0.007248688,0.001064157,0.001138815,0.001411637,0.0009585905,0.00145907,0.0008600373,0.003078857,0.006106489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005327084,"about_ca_system_score_gemma":0.001106451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003753513,"about_ca_topic_score_gemma":0.0009417501,"domain_scores_codex":[0.9931647,0.002470451,0.0007464855,0.0008454705,0.00250438,0.000268484],"domain_scores_gemma":[0.9943941,0.002239967,0.0006345536,0.000956639,0.001512207,0.0002625068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002242462,0.0002419914,0.00151798,0.000642889,0.00005039411,0.0002192031,0.0002553142,0.0002305276,0.9706961,0.0018432,0.001433639,0.02264453],"study_design_scores_gemma":[0.00007577537,0.0009373997,0.003040349,0.0001137054,0.0001194278,0.001443924,0.00005332821,0.008203526,0.9609357,0.00076324,0.02424594,0.00006768838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.07183079,0.003907509,0.9030561,0.0002014837,0.0005009786,0.002605831,0.001568447,0.003534501,0.01279439],"genre_scores_gemma":[0.1105284,0.00377499,0.851525,0.0003173617,0.0002358987,0.004047367,0.007312184,0.0007144629,0.02154438],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.008135125,"threshold_uncertainty_score":0.02721465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03353090578844048,"score_gpt":0.3133231834123107,"score_spread":0.2797922776238703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}