{"id":"W2075048533","doi":"10.1016/j.toxlet.2005.03.012","title":"Photogenotoxicity of hypericin in HaCaT keratinocytes: Implications for St. John's Wort supplements and high dose UVA-1 therapy","year":2005,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Tenovus","keywords":"Hypericin; Hypericum perforatum; Phototoxicity; HaCaT; Hyperforin; Hypericum; Dermatology; Pharmacology; Photodynamic therapy; Medicine; Chemistry; Traditional medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003252859,0.0001814368,0.0004605488,0.0002238977,0.00009352292,0.00000646825,0.0001411347,0.00009171059,0.0001270024],"category_scores_gemma":[0.00007924106,0.0001576128,0.00006369557,0.000195545,0.0003146967,0.00006871483,0.00005966569,0.0002089126,0.000002196011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000182084,"about_ca_system_score_gemma":0.00007277957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001047981,"about_ca_topic_score_gemma":0.0003795777,"domain_scores_codex":[0.9986385,0.00007507006,0.0003847802,0.0003375139,0.0001279459,0.0004362414],"domain_scores_gemma":[0.999149,0.0002907207,0.0001014149,0.0003070839,0.00005906843,0.00009272811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006779778,0.0003500103,0.04479934,0.00003130615,0.0001515245,0.000004344653,0.0005272718,0.00001207694,0.9415107,0.00009003802,0.003126081,0.008719319],"study_design_scores_gemma":[0.01000065,0.001056381,0.8298578,0.00003385496,0.00003772466,0.00003272244,0.0001187642,0.0001733671,0.1470728,0.0001749546,0.0112205,0.0002204333],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660318,0.0005121005,0.0001175945,0.03109791,0.00004035553,0.00196653,0.0001617535,0.00002858352,0.00004336287],"genre_scores_gemma":[0.9869079,0.001003722,0.002562903,0.008571826,0.00008918206,0.0007004873,0.0000673655,0.00002438604,0.00007224012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7944379,"threshold_uncertainty_score":0.6427262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03414491580109569,"score_gpt":0.3407934575882623,"score_spread":0.3066485417871666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}