{"id":"W2075075335","doi":"10.1016/s1074-5521(01)00078-3","title":"Peptides that mimic glycosaminoglycans: high-affinity ligands for a hyaluronan binding domain","year":2001,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre","funders":"University of Utah; Utah State University; U.S. Department of State; U.S. Department of Defense","keywords":"Peptide; Glycosaminoglycan; Receptor; Biochemistry; Hyaluronic acid; Fluorescence anisotropy; Chemistry; Hyaluronidase; Cyclic peptide; Binding site; Cell adhesion; Amino acid; Stereochemistry; Biology; Cell; Enzyme; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001823412,0.0003499961,0.0002319211,0.0001108172,0.0001599339,0.0002857462,0.0003343379,0.000436485,0.001769685],"category_scores_gemma":[0.0002493559,0.0001587474,0.0001889803,0.0001307031,0.000162525,0.0002495098,0.0002192923,0.0006246571,0.0006803721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355698,"about_ca_system_score_gemma":0.0001111837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002390961,"about_ca_topic_score_gemma":0.0002825872,"domain_scores_codex":[0.9999006,0.0000221634,0.000006442418,0.00001545058,0.00002246842,0.00003297032],"domain_scores_gemma":[0.9998652,0.00003722356,0.00002093398,0.000009159483,0.00001380443,0.00005357984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001968178,0.00004240852,0.0001089461,0.00003961199,0.000009261481,0.0001312777,0.00001514847,0.0006105869,0.9963786,0.0003146229,0.00009701983,0.002055709],"study_design_scores_gemma":[0.00007169083,0.0003730518,0.0006522005,0.000006849453,0.00001971846,0.000472015,0.00001795189,0.001643206,0.9923092,0.00013783,0.004284881,0.00001131588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848912,0.001681298,0.009552021,0.0001925844,0.0001248474,0.0001026149,0.0002109425,0.00006090272,0.003183588],"genre_scores_gemma":[0.9881085,0.0009977161,0.007341845,0.0003568964,0.00003547518,0.00006213523,0.0004169996,0.00002237353,0.00265805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001769685,"threshold_uncertainty_score":0.005920231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425794635499644,"score_gpt":0.288509333849756,"score_spread":0.2642513874947596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}