{"id":"W2075089790","doi":"10.1097/fpc.0b013e3283330767","title":"Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3","year":2009,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institute of Environmental Health Sciences; National Institute on Deafness and Other Communication Disorders; National Institutes of Health","keywords":"Glucuronidation; Complementary DNA; Molecular biology; Recombinant DNA; Biology; genomic DNA; Exon; Glucuronosyltransferase; UGT2B7; Chemistry; Biochemistry; Gene; Enzyme; Microsome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003332282,0.0004841397,0.000450204,0.0003630309,0.0002894588,0.0004913656,0.0002940794,0.0005446608,0.001831244],"category_scores_gemma":[0.0003356522,0.0002161979,0.0005677214,0.000745322,0.0002961482,0.0002954561,0.0001757007,0.0005933676,0.001346271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004226815,"about_ca_system_score_gemma":0.0004404754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001216342,"about_ca_topic_score_gemma":0.001225609,"domain_scores_codex":[0.9997475,0.00003446514,0.00002141257,0.00008023738,0.00008226724,0.00003420036],"domain_scores_gemma":[0.9998753,0.00001945966,0.00002372023,0.00001707862,0.0000353822,0.00002907137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173649,0.00004360527,0.0006517573,0.0001287516,0.00001817253,0.000145227,0.00002920862,0.0002016856,0.9936215,0.0001888362,0.0003882842,0.004365707],"study_design_scores_gemma":[0.0001136601,0.000396975,0.01563955,0.00002512891,0.0001437707,0.003359822,0.00004802035,0.004682197,0.9276226,0.0002209777,0.04771501,0.00003222225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9245778,0.01248323,0.04357297,0.001174836,0.0003987479,0.0005653131,0.01120131,0.0006025499,0.005423255],"genre_scores_gemma":[0.8241007,0.01189627,0.08897986,0.0004446764,0.0003789949,0.000701619,0.05055974,0.0003836021,0.02255461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001831244,"threshold_uncertainty_score":0.006126106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05646111701490544,"score_gpt":0.3641562268324516,"score_spread":0.3076951098175462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}