{"id":"W2075089790","doi":"10.1097/fpc.0b013e3283330767","title":"Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3","year":2009,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institute of Environmental Health Sciences; National Institute on Deafness and Other Communication Disorders; National Institutes of Health","keywords":"Glucuronidation; Complementary DNA; Molecular biology; Recombinant DNA; Biology; genomic DNA; Exon; Glucuronosyltransferase; UGT2B7; Chemistry; Biochemistry; Gene; Enzyme; Microsome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004041025,0.0004132613,0.0004447376,0.0002307551,0.000445754,0.00008851355,0.0001159533,0.0002218465,0.0001581535],"category_scores_gemma":[0.000007413456,0.0004044701,0.00003675379,0.0001921537,0.000362692,0.0001406483,0.00007130273,0.0005790766,0.000003886066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003227685,"about_ca_system_score_gemma":0.00006833211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005766203,"about_ca_topic_score_gemma":0.000008884029,"domain_scores_codex":[0.9979239,0.0002216857,0.0005754511,0.0006240109,0.0001698304,0.0004851298],"domain_scores_gemma":[0.9990348,0.00007198167,0.0001721555,0.0001499917,0.0001043785,0.0004666595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004101909,0.0002520539,0.05411625,0.00004226929,0.0000733104,0.00001399534,0.000832009,0.0006354246,0.894828,0.0008535615,0.00009432255,0.04784869],"study_design_scores_gemma":[0.01381265,0.0005242707,0.4015154,0.00005380918,0.0006685369,0.0003051326,0.0003270818,0.01465742,0.4433791,0.001991371,0.1213452,0.001420003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919281,0.004383583,0.001483281,0.0007181045,0.0003709182,0.0005471769,0.0001887328,0.00004564304,0.0003344485],"genre_scores_gemma":[0.9889349,0.007407118,0.001269977,0.00180344,0.0003203546,0.00002984636,0.0001391034,0.00003696188,0.00005833175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4514488,"threshold_uncertainty_score":0.9998407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05646111701490544,"score_gpt":0.3641562268324516,"score_spread":0.3076951098175462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}