{"id":"W2075119331","doi":"10.1007/s10238-010-0112-7","title":"Gene delivery of soluble vascular endothelial growth factor receptor-1 (sFlt-1) inhibits intra-plaque angiogenesis and suppresses development of atherosclerotic plaque","year":2010,"lang":"en","type":"article","venue":"Clinical and Experimental Medicine","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Angiogenesis; Transfection; Recombinant DNA; Vascular endothelial growth factor; Immunohistochemistry; Tissue factor; Genetic enhancement; Vulnerable plaque; Medicine; Kinase insert domain receptor; Western blot; Pathology; Vascular endothelial growth factor A; Molecular biology; Biology; Cancer research; Internal medicine; Gene; VEGF receptors; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002311825,0.0001889791,0.0003991873,0.00003611999,0.00006305045,0.000004445264,0.0001197681,0.0002196386,0.0001420933],"category_scores_gemma":[0.00009118209,0.0001446721,0.0001000673,0.00004720906,0.0006483273,0.000007065489,0.0001538598,0.00008348629,0.000001340097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004556112,"about_ca_system_score_gemma":0.00007150486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005158581,"about_ca_topic_score_gemma":0.00002162935,"domain_scores_codex":[0.9986637,0.00004836306,0.0005880443,0.0003648826,0.0001555911,0.0001793756],"domain_scores_gemma":[0.9993318,0.00006975445,0.0001504348,0.000192612,0.00008757892,0.0001678078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001971822,0.000168479,0.0228925,0.00004777684,0.0001313734,5.880204e-7,0.0002497382,2.045267e-7,0.9734559,0.0000238299,0.0003517377,0.002480676],"study_design_scores_gemma":[0.001630184,0.0006515271,0.01083112,0.00005600929,0.00002747828,0.000005547848,0.0001928159,0.000003302184,0.9829877,0.000008523123,0.003446992,0.0001587844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993885,0.005232221,0.00007493795,0.0000857383,0.0004741864,0.000174242,0.00003038419,0.000006121621,0.00003721014],"genre_scores_gemma":[0.9946654,0.002477798,0.002170952,0.0001382305,0.0004187192,0.00002100582,0.00004858446,0.00002162199,0.00003771791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01206138,"threshold_uncertainty_score":0.5899557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02507898501040516,"score_gpt":0.2976741607745743,"score_spread":0.2725951757641691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}