{"id":"W2075126931","doi":"10.1016/j.exphem.2008.06.001","title":"Molecular profiling of candidate human hematopoietic stem cells derived from human embryonic stem cells","year":2008,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Robarts Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Haematopoiesis; Stem cell; Embryonic stem cell; Cell biology; Progenitor cell; Homing (biology); Wnt signaling pathway; Immunology; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000130371,0.000405336,0.000655017,0.0001161767,0.000274354,0.00001575913,0.0006024517,0.0003485449,0.0001066308],"category_scores_gemma":[0.000001719279,0.0004245933,0.0002393048,0.0001242872,0.000463225,0.0000100255,0.000516824,0.0002151607,0.0000764611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006536672,"about_ca_system_score_gemma":0.0001107468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001316213,"about_ca_topic_score_gemma":0.00001235053,"domain_scores_codex":[0.9971694,0.0002666648,0.0006506335,0.0008525898,0.0003772964,0.0006833727],"domain_scores_gemma":[0.9985393,0.00002374254,0.0002793528,0.0008506036,0.00008529198,0.0002217129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007549879,0.0003314354,0.0009793832,0.00008529617,0.0001385566,0.0002481743,0.000283923,0.00002938197,0.9967346,0.0007520399,0.0003320248,0.000009755174],"study_design_scores_gemma":[0.001341695,0.0004448923,0.00003939938,0.00004061736,0.00001762183,0.0001638639,0.000761005,0.00003420065,0.9965811,0.00002045708,0.0001697709,0.000385397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900507,0.008227401,0.0002386672,0.00001934401,0.0001704285,0.0005973868,0.00005187612,0.00003769004,0.0006065177],"genre_scores_gemma":[0.9985088,0.0000576288,0.0004091575,0.00006433098,0.00005473982,0.00009515177,0.0001474802,0.00008182059,0.000580926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008458076,"threshold_uncertainty_score":0.9998206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02040430155990714,"score_gpt":0.2876308438360388,"score_spread":0.2672265422761316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}