{"id":"W2075126931","doi":"10.1016/j.exphem.2008.06.001","title":"Molecular profiling of candidate human hematopoietic stem cells derived from human embryonic stem cells","year":2008,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Robarts Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Haematopoiesis; Stem cell; Embryonic stem cell; Cell biology; Progenitor cell; Homing (biology); Wnt signaling pathway; Immunology; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001239193,0.0001935187,0.0001779871,0.0005057353,0.000175124,0.0003657181,0.0001575112,0.0001969547,0.001336263],"category_scores_gemma":[0.0001697026,0.0001087377,0.0001544798,0.0004217053,0.00009349798,0.0001034964,0.0001073516,0.0002160701,0.000456602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001255556,"about_ca_system_score_gemma":0.0001758809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004081744,"about_ca_topic_score_gemma":0.0006217525,"domain_scores_codex":[0.999921,0.00001412684,0.000005720065,0.00001734251,0.00002337039,0.00001846495],"domain_scores_gemma":[0.9999235,0.00002660639,0.00001133889,0.000005807499,0.00001645809,0.00001633221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002012485,0.00001371563,0.001572759,0.00002206554,0.000007345529,0.00005017433,0.00001663622,0.0000651956,0.9960161,0.0001522856,0.00005627248,0.001826144],"study_design_scores_gemma":[0.00002085489,0.0002295755,0.03538654,0.000006478733,0.00006216189,0.000330561,0.00008004338,0.001172341,0.9590014,0.0001088884,0.003597497,0.000003570292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890636,0.001264435,0.006151844,0.00006925826,0.00001314822,0.0000520287,0.001246639,0.00004641592,0.002092678],"genre_scores_gemma":[0.9827012,0.001105794,0.007989425,0.00007659022,0.00001345482,0.00007083153,0.004519813,0.00002790846,0.003494948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001336263,"threshold_uncertainty_score":0.004470289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02040430155990714,"score_gpt":0.2876308438360388,"score_spread":0.2672265422761316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}