{"id":"W2075185325","doi":"10.1016/s0969-9961(03)00002-0","title":"Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies","year":2003,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"Korea Science and Engineering Foundation","keywords":"Microglia; Programmed cell death; Reactive oxygen species; Trolox; Biology; Cell biology; In vivo; Neuroprotection; Terminal deoxynucleotidyl transferase; Apoptosis; Biochemistry; Pharmacology; Oxidative stress; Immunology; TUNEL assay; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006196264,0.001069408,0.0004394127,0.0005384414,0.0007462985,0.0003528123,0.000405743,0.0008833173,0.001535577],"category_scores_gemma":[0.0003445399,0.0003037589,0.0005425261,0.0004141183,0.0008218929,0.0005726846,0.0002711112,0.001253154,0.0004581118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005631965,"about_ca_system_score_gemma":0.0004336797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002067249,"about_ca_topic_score_gemma":0.002852804,"domain_scores_codex":[0.9995766,0.0001202591,0.00002483775,0.00003498765,0.0001007841,0.0001424804],"domain_scores_gemma":[0.9996737,0.0001012059,0.00008020584,0.00004850633,0.00005307282,0.00004330901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009878088,0.0001701412,0.0001465607,0.00008534562,0.00001142937,0.0002249531,0.00008375676,0.00005603581,0.9974633,0.0001407362,0.00003384331,0.0005961003],"study_design_scores_gemma":[0.00008863767,0.002196365,0.002595533,0.00001513044,0.00004353238,0.0006600125,0.0001077194,0.0004293448,0.9927537,0.0001443569,0.0009585201,0.000007175452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838918,0.008641217,0.004592617,0.0002362738,0.00008254,0.00008575118,0.0002168036,0.00003777508,0.002215148],"genre_scores_gemma":[0.9881352,0.005223115,0.00285034,0.00007918692,0.00008837638,0.0001159426,0.0004074975,0.00001752903,0.003082776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002067249,"threshold_uncertainty_score":0.005136967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02873674199453376,"score_gpt":0.2601266396759019,"score_spread":0.2313898976813682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}