{"id":"W2075204962","doi":"10.1016/j.jpba.2012.03.005","title":"Comparison of solid phase microextraction versus spectroscopic techniques for binding studies of carbamazepine","year":2012,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Solid-phase microextraction; Chromatography; Cooperativity; Fluorescence; Mass spectrometry; Analytical Chemistry (journal); Gas chromatography–mass spectrometry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004977397,0.0001038935,0.0005867919,0.0002528218,0.00005271016,0.000004088766,0.00008505534,0.00007730559,0.00003349458],"category_scores_gemma":[0.0002403353,0.00007213126,0.0003845636,0.0003533841,0.0002571271,0.00001344272,0.0000547014,0.0001117186,2.452302e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001802651,"about_ca_system_score_gemma":0.0000176704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004052827,"about_ca_topic_score_gemma":0.000001913517,"domain_scores_codex":[0.9987937,0.00004542446,0.0006700718,0.000106488,0.0002108766,0.0001734432],"domain_scores_gemma":[0.9988919,0.00009029771,0.0005051075,0.00007131944,0.0003062591,0.0001351192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008924729,0.0006165401,0.005622723,0.0000831474,0.005280016,5.35267e-7,0.00008212008,9.489224e-7,0.9767396,0.00001025169,0.0006209842,0.01005068],"study_design_scores_gemma":[0.001234822,0.001336551,0.0002243161,0.00003348016,0.003742955,0.000004485488,0.0008191422,0.0003339222,0.9790413,0.00000872695,0.01313748,0.00008283091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605677,0.01037925,0.02823207,0.0004660907,0.0002229254,0.00008244493,0.00003590433,0.000002315893,0.00001131648],"genre_scores_gemma":[0.9942213,0.00324192,0.002066528,0.00002590831,0.0003984026,0.000003934666,0.00001602739,0.000004041857,0.0000219533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0336536,"threshold_uncertainty_score":0.2941428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09230211541049489,"score_gpt":0.5169344297442934,"score_spread":0.4246323143337985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}