{"id":"W2075222439","doi":"10.1139/v04-174","title":"Stereoselective synthesis of multiply substituted [1,2]oxazinan-3-ones via ring-closing metathesis","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Dihydroxylation; Acryloyl chloride; Diastereomer; Ring-closing metathesis; Allylic rearrangement; Metathesis; Tricyclohexylphosphine; Stereochemistry; Medicinal chemistry; Organic chemistry; Enantioselective synthesis; Catalysis; Phosphine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006195651,0.0003974183,0.0008129518,0.000126704,0.0001418756,0.0000528492,0.0008094435,0.0003592155,0.004355283],"category_scores_gemma":[0.002573588,0.0004154015,0.000401411,0.0003150194,0.0003375421,0.0002040986,0.00003263971,0.0005873894,0.00001012396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007369283,"about_ca_system_score_gemma":0.001648112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005151472,"about_ca_topic_score_gemma":0.0004018208,"domain_scores_codex":[0.9974918,0.00004767268,0.00109045,0.0003420609,0.0004110966,0.0006169239],"domain_scores_gemma":[0.9963341,0.0007009662,0.000956699,0.000574966,0.000516213,0.00091701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004869258,0.00006289237,0.001356674,0.0003270802,0.0002842506,0.000102592,0.0004280512,0.00005175337,0.9711456,0.000002308704,0.0001429767,0.02604708],"study_design_scores_gemma":[0.0005391368,0.000006325402,0.0001789229,0.0004596123,0.0002680657,0.00097613,0.0005158349,0.0001338488,0.9915763,0.00006330786,0.004905718,0.000376825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793088,0.00145573,0.0006971027,0.0004164236,0.0001187568,0.00004370511,0.00007440256,0.00002666211,0.0178584],"genre_scores_gemma":[0.9881666,0.0000296595,0.01048643,0.00002688442,0.0006413336,0.000005189457,0.000003256035,0.00007301012,0.0005676856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02567026,"threshold_uncertainty_score":0.9998298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388067562866911,"score_gpt":0.2363076324907502,"score_spread":0.2224269568620811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}