{"id":"W2075235600","doi":"10.1242/jcs.042531","title":"Knockout of GARPs and the β-subunit of the rod cGMP-gated channel disrupts disk morphogenesis and rod outer segment structural integrity","year":2009,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute","keywords":"Homomeric; Biology; Protein subunit; Cell biology; Visual phototransduction; Morphogenesis; Biophysics; Biochemistry; Retinal; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401835,0.0005090306,0.0002612623,0.0003254005,0.0001384798,0.0002610487,0.000354521,0.0004198315,0.001273494],"category_scores_gemma":[0.000130595,0.0002636191,0.0002663664,0.0001396941,0.0003612829,0.0002005191,0.0003464399,0.0006364247,0.0002896907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002849018,"about_ca_system_score_gemma":0.000223453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110662,"about_ca_topic_score_gemma":0.001240826,"domain_scores_codex":[0.9997944,0.00001693772,0.00003281156,0.00005574402,0.00004967546,0.00005039724],"domain_scores_gemma":[0.9995847,0.00006408516,0.000156168,0.00003189366,0.00001574223,0.0001473126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005649745,0.00001411608,0.0001085593,0.00001172986,0.000003072234,0.00004939214,0.00001028869,0.00005738514,0.9992974,0.00006832354,0.000008131828,0.0003150481],"study_design_scores_gemma":[0.00002765789,0.0002050934,0.009033699,0.00001162001,0.00002363978,0.0002974329,0.0000616134,0.002156639,0.9870098,0.00007990502,0.00108486,0.000008155232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971126,0.0002602005,0.001532366,0.00004497009,0.00001827715,0.00001530178,0.0003297956,0.0000908102,0.000595597],"genre_scores_gemma":[0.9945676,0.0002365949,0.001635193,0.00003821261,0.000004198901,0.00002353474,0.0003108055,0.00007217527,0.003111817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001273494,"threshold_uncertainty_score":0.004260242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006368540711389362,"score_gpt":0.2294586732378218,"score_spread":0.2230901325264324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}