{"id":"W2075268562","doi":"10.1007/s00702-007-0697-5","title":"Effect of aldehydes derived from oxidative deamination and oxidative stress on β-amyloid aggregation; pathological implications to Alzheimer’s disease","year":2007,"lang":"en","type":"article","venue":"Journal of Neural Transmission","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Oxidative deamination; Chemistry; Oxidative stress; Lipid peroxidation; Methylglyoxal; Biochemistry; Senile plaques; Monoamine oxidase; Thioflavin; Malondialdehyde; Methylamine; Alzheimer's disease; Pathology; Enzyme; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005119565,0.0005737399,0.0002821255,0.0003894672,0.0003964586,0.0002938784,0.0002251676,0.0004925292,0.001713634],"category_scores_gemma":[0.0004459577,0.0002415635,0.0004291579,0.0001999117,0.0003737981,0.0006115384,0.0002873944,0.0004813911,0.0001698906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002495264,"about_ca_system_score_gemma":0.0001960084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009689716,"about_ca_topic_score_gemma":0.0009357076,"domain_scores_codex":[0.9998523,0.00005983876,0.00001248292,0.00001762877,0.00001625024,0.00004144787],"domain_scores_gemma":[0.9996499,0.00008313057,0.00006297957,0.00003360416,0.00007047837,0.0001000643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03740244,0.0006095659,0.004416088,0.0003546379,0.0003122067,0.001433224,0.0002466129,0.0005243053,0.9410998,0.0009129222,0.0002198937,0.01246822],"study_design_scores_gemma":[0.0001992846,0.005492688,0.01361267,0.00002406672,0.000213989,0.0009176179,0.0001724039,0.0007703289,0.9757319,0.0005808228,0.002260304,0.00002394232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992174,0.005510332,0.0006647594,0.0001037725,0.00007280904,0.00001423373,0.00008829569,0.00001456724,0.001357233],"genre_scores_gemma":[0.9976661,0.001135362,0.0003699156,0.00005154066,0.00002669774,0.000004250884,0.00007637015,0.000003443082,0.0006664456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713634,"threshold_uncertainty_score":0.005732656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03752391911947633,"score_gpt":0.3593074307141501,"score_spread":0.3217835115946737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}