{"id":"W2075315824","doi":"10.1016/j.scitotenv.2014.09.103","title":"Ecotoxicity of ketoprofen, diclofenac, atenolol and their photolysis byproducts in zebrafish (Danio rerio)","year":2014,"lang":"en","type":"article","venue":"The Science of The Total Environment","topic":"Pharmaceutical and Antibiotic Environmental Impacts","field":"Environmental Science","cited_by":138,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Ministério da Ciência, Tecnologia e Ensino Superior; Public Health Agency of Canada","keywords":"Diclofenac; Ketoprofen; Chemistry; Atenolol; Oxidative stress; Lipid peroxidation; Superoxide dismutase; Catalase; Toxicity; Glutathione; Pharmacology; Environmental chemistry; Biochemistry; Chromatography; Enzyme; Biology; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001130719,0.0001963723,0.0002517451,0.00003342681,0.0002140829,0.0000156611,0.0008564717,0.00004251096,0.0003539046],"category_scores_gemma":[0.00008371302,0.000101541,0.00007721512,0.0003642328,0.004921163,0.0002350559,0.001424039,0.0001900717,0.00003931293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001105289,"about_ca_system_score_gemma":0.000007958372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001281064,"about_ca_topic_score_gemma":0.000003425822,"domain_scores_codex":[0.9981239,0.0001346782,0.0003376439,0.0004333987,0.0005437071,0.0004267152],"domain_scores_gemma":[0.9988994,0.00007423242,0.0001967039,0.000695753,0.000001412926,0.0001325157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001788476,0.0001542802,0.004072445,0.00001029583,0.000006538923,2.789054e-7,0.0006089918,0.003722508,0.9885545,0.00007080108,0.0000141338,0.002767285],"study_design_scores_gemma":[0.0002272972,0.00007821539,0.3091665,0.00002339142,0.00001314589,0.000007453289,0.000177258,0.004152947,0.6851856,0.000792049,0.00005996368,0.0001162205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954859,0.00004863991,0.00001202682,0.001402249,0.000081576,0.0003575299,0.000007052703,0.000006709251,0.002598288],"genre_scores_gemma":[0.9993519,0.00006703737,0.0001248562,0.0001031825,0.00001184118,0.000004353027,3.110766e-7,0.000009669082,0.0003268186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.305094,"threshold_uncertainty_score":0.9977869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01167837408731664,"score_gpt":0.2175894551698013,"score_spread":0.2059110810824847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}