{"id":"W2075337932","doi":"10.1016/s1063-4584(09)60471-4","title":"450 MATRIPTASE IS A COLLAGENASE INDUCER AND ACTIVATOR: IMPLICATIONS FOR CARTILAGE MATRIX DEGRADATION IN OSTEOARTHRITIS","year":2009,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Osteoarthritis; Inducer; Collagenase; Chemistry; Cartilage; Bone matrix; Activator (genetics); Cell biology; Medicine; Biology; Biochemistry; Anatomy; Pathology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003377903,0.0002826462,0.0003176678,0.0003014153,0.0003473607,0.0009922335,0.0002472805,0.0005063752,0.002081007],"category_scores_gemma":[0.0002369769,0.0001676011,0.0003189803,0.0001686145,0.0003097656,0.0004778452,0.000206742,0.0004931185,0.000915336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000394384,"about_ca_system_score_gemma":0.0002848966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006287402,"about_ca_topic_score_gemma":0.0006594612,"domain_scores_codex":[0.9998391,0.00002778566,0.00001457484,0.0000268767,0.00005623552,0.0000353957],"domain_scores_gemma":[0.9998506,0.00001816603,0.00004274107,0.000008092392,0.00003231818,0.00004798007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001167883,0.0001191845,0.002328856,0.0002705336,0.00005469117,0.001199263,0.00008482827,0.0001677265,0.9559228,0.004152226,0.001445342,0.03308658],"study_design_scores_gemma":[0.0000781161,0.001244446,0.0365212,0.00004603846,0.0001483851,0.009141306,0.0002481024,0.001560575,0.8814549,0.003018185,0.06649955,0.00003925415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7048082,0.2293733,0.02326532,0.005797743,0.001336644,0.0001411555,0.001375702,0.0004098623,0.03349202],"genre_scores_gemma":[0.9497881,0.02822764,0.005174275,0.0005152322,0.0007393765,0.00002868216,0.0007966306,0.00003115938,0.01469894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002081007,"threshold_uncertainty_score":0.006961644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01538507022170745,"score_gpt":0.277887557314683,"score_spread":0.2625024870929756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}